Негормональна терапія клімактеричних розладів

Т. Ф Татарчук; О. О. Єфименко; О. В. Занько

doi:10.18370/2309-4117.2016.30.75-80

Authors

Т. Ф Татарчук SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”, Ukraine https://orcid.org/0000-0002-5498-4143
О. О. Єфименко SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”, Ukraine https://orcid.org/0000-0003-1228-0911
О. В. Занько SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”, Ukraine https://orcid.org/0000-0002-1393-4115

DOI:

https://doi.org/10.18370/2309-4117.2016.30.75-80

Keywords:

climacteric syndrome, non-hormonal therapy, Klimaktoplan, Valesan

Abstract

The aim of the study was to optimize the treatment of climacteric disorders, taking into account the nature of psychopathological disorders. 100 women 50–55 years old with climacteric disorders of mild to moderate severity were examined. Depending on the treatment women were divided into 3 groups: I group – 30 women received a complex homeopathic medication Klimaktoplan within 3 months, group II – 34 women received monotherapy with Valesan for 3 months, III group – 36 patients received both these drugs during the same period.

Assessment of the severity of climacteric syndrome was held in accordance with the Menopausal Rating Scale (MRS) before and after treatment. To assess the level of anxiety used Spielberger-Hanin questionnaire. To identify insomnia disorders was used questionnaire of scoring assay for subjective sleep characteristics proposed by Y.I. Levin.

Study of climacteric manifestations showed that the average total MRS scale score decreased in all groups after treatment. However, the best results were demonstrated in patients group III. Against the background of neuro-vegetative disorders reduction and improve sleep parameters was significantly reduced physical and mental exhaustion.

Monitoring the frequency and nature of personal anxiety during therapy showed statistically significant decreasing proportion of patients with high and low levels in all groups and increasing the number of women with a moderate level. The largest share of women with secondary (optimal) level of personal anxiety was observed in group III, which was administered Klimaktoplan and Valesan. Also, in all groups patients significantly reduced the severity of sleep disorders, but the most in group III.

Study results indicate the feasibility complex use of Klimaktoplan and Valesan for climacteric syndrome treatment. Complex use these drugs results in improved sleep, reduced anxiety levels, causes a decrease in hot flushes number and improve the quality of women life.

Author Biographies

Т. Ф Татарчук, SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”

MD, professor, corresponding member of the NAMS of Ukraine, deputy director for research work, chief of the Endocrine Gynecology Department

О. О. Єфименко, SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”

PhD, senior researcher of the Endocrine Gynecology Department

О. В. Занько, SI “Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”

Graduate student of the Endocrine Gynecology Department

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