The influence of thyroid disorders upon the female reproductive function. modern possibilities of phytotherapy

Authors

  • В. І. Паньків Ukrainian Scientific and Practical Centre of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues, Health Ministry of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0002-9205-9530

DOI:

https://doi.org/10.18370/2309-4117.2016.27.52-57

Keywords:

reproductive system, thyroid gland, phytotherapy, TazalokТМ

Abstract

The article summarizes information on aspects of the women’s reproductive system functions disorders on the background of thyroid diseases. Influence of thyroid gland on the reproductive system is realized through peripheral endocrine glands (gonads and adrenal glands), and through the central structure (neurotransmitter and the hypothalamic-pituitary system).

Any dysfunction of the thyroid gland (hypothyroidism or hyperthyroidism) can lead disruption of the menstrual function, cause infertility and miscarriage. Girls hypothyroidism marked menstrual disorders, delayed puberty, amenorrhea.

Autoimmune thyroiditis as one of the most common diseases of the thyroid gland is associated with miscarriages. Risk of thyroid dysfunction is increased in such patients in pregnancy.

Due to the effect of human chorionic gonadotropin and estrogen on the thyroid gland during pregnancy, there may be transient changes in thyroid hormone levels, which requires differential diagnosis.

Thyroid hormones are essential for normal functioning of the mammary glands, affecting their structural elements. Reduced thyroid function significantly increases the risk of mastitis.

Protective effect in the treatment of breast diseases has potassium iodide drugs.

More than half of women with infertility observed pathology of the thyroid gland, sometimes without clinical manifestations. Every second woman’s menstrual cycle and/or infertility precede thyroid diseases.

All women who live in Ukraine (iodine deficiency region) should appoint an individual iodine prophylaxis on the stage of pregnancy planning (potassium iodide drugs at a dose 200 mg/day).

Thyroid function should monitor in women with menstrual irregularities, infertility and miscarriage. The most informative is evaluation of thyroid-stimulating hormone and free thyroxine and triiodothyronine in blood serum.

TazalokТМ as a complex herbal drug is recommended for women with concomitant thyroid pathology and dyshormonal genital diseases.

Author Biography

В. І. Паньків, Ukrainian Scientific and Practical Centre of Endocrine Surgery, Transplantation of Endocrine Organs and Tissues, Health Ministry of Ukraine, Kyiv

MD, professor, head of the Clinical Thyroidology Department

References

  1. Ventskovskyi, B.M., Yarotskyi, M.E., Yarotska, I.V. “Thyrotropic activity of the pituitary and functional state of thyroid system in women with benign uterine diseases in combination with thyroid gland disorders.” Science works collection of the Association of Obstetricians and Gynecologists of Ukraine (2006): 78–82.
  2. Ventskovska, I.B., Yefymenko, O.A. “Hyperprolactinemic states in gynecologist practice and methods of their treatment.” Reproductive Health of Women 3.15 (2008): 71–6.
  3. Pasiechko, N.V., Gnat, S.V., Svystun, I.I., Naumova, L.V. “Subclinical hypothyroidism effect at women’s reproductive function and efficiency of its correction.” International Journal of Endocrinology 1.65 (2015): 98–101.
  4. Pashkovska, N.V. “Thyroid disease and pregnancy.” International Journal of Endocrinology 8.48 (2012): 78–82.
  5. Tatarchuk, T.F., Davydova, Y.V., Kosianchuk, N.Y. “Thyroid homeostasis and reproductive health of women.” News of Medicine and Pharmacy 13 (2007): 14–15.
  6. Fadeev, V.V. “According to the materials of the American Thyroid Association clinical guidelines for the diagnosis and treatment of thyroid disease during pregnancy and postpartum period.” Clinical and experimental thyroidology 8.1 (2012): 7–18.
  7. Endocrine gynecology (clinical essays). Part I. / Ed. by T.F. Tatarchuk, Y.P. Sokolskyi. Kyiv. Zapovіt (2006): 303 p.
  8. Abalovich, M., Gutierrez, S., Alcaraz, G., et al. “Overt and subclinical hypothyroidism complicating pregnancy.” Thyroid 12.1 (2002): 63–8.
  9. Glinoer, D. “Clinical and biological consequences of iodine deficiency during pregnancy (Review).” Endocr Dev 10 (2007): 62–85.
  10. Haddow, J.E., Cleary-Goldman, J., McClain, M.R., et al. “Thyroperoxidase and thyroglobulin antibodies in early pregnancy and preterm delivery.” Obstet Gynecol 116.1 (2010): 58–62.
  11. Krassas, G.E., Poppe, K., Glinoer, D. “Thyroid Function and Human Reproductive Health.” Endocr Rev 31 (2010): 702–55.
  12. Lazarus, J.H. “Epidemiology and prevention of thyroid disease in pregnancy.” Thyroid 12.10 (2002): 861–5.
  13. Negro, R., Schwartz, A., Gismondi, R., et al. “Universal screening versus case finding for detection and treatment of thyroid hormonal dysfunction during pregnancy.” J Clin Endocrinol Metab 95.4 (2010): 1699–707.
  14. Patil-Sisodia, K., Mestman, J.H. “Graves hyperthyroidism and pregnancy: a clinical update.” Endocr Pract 16.1 (2010): 118–29.
  15. Stagnaro-Green, A. “Оptimal care of the pregnant woman with thyroid disease.” J Clin Endocrinol Metab 97.8 (2012): 2619–22.
  16. Stagnaro-Green, А., Pearce, E. “Thyroid disorders in pregnancy.” Nature Reviews Endocrinology 8 (2012): 650–8.
  17. Yassa, L., Marqusee, E., Fawcett, R., et al. “Thyroid hormone early adjustment in pregnancy (the therapy) trial.” J Clin Endocrinol Metab 95.7 (2010): 3234–41.

Downloads

Published

2016-04-05

How to Cite

Паньків, В. І. (2016). The influence of thyroid disorders upon the female reproductive function. modern possibilities of phytotherapy. REPRODUCTIVE ENDOCRINOLOGY, (27), 52–57. https://doi.org/10.18370/2309-4117.2016.27.52-57

Issue

No. 27 (2016)

Section

Reproductology

License

Copyright (c) 2016 В. І. Паньків

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.