Impact of use Tivortin on life quality and condition of the fetus in pregnant women with heart failure

Authors

  • А. Ю. Ліманська Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine, Ukraine
  • Ю. В. Давидова Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine, Ukraine
  • В. А. Слободський National Scientific Centre "Institute of Cardiology named after N.D. Strazhesko" of the NAMS of Ukraine, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2014.19.37-39

Keywords:

pregnancy, heart failure, nitric oxide, L-arginine, Tivortin

Abstract

A study to examine the quality of life of the woman and the fetus in pregnant with heart failure as a result of the drug Tivortin use was performed.

There were examined 40 pregnant women with NYHA II–III heart failure on a background of cardiovascular disease and signs of fetal condition disorders. All patients received standard therapy of heart failure. Pregnant were divided into two groups of 20 women in each. In the main group to the basic therapy was additionally appointed arginine hydrochloride (drug Tivortin). The comparison group continued intake a basic therapy.

The results showed that the addition Tivortin to the basic treatment of pregnant women with heart failure improves quality of their life and overall health, and a significant improvement of the fetus in these women confirms the effectiveness of this therapy

Author Biographies

А. Ю. Ліманська, Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine

PhD, senior researcher, Obstetric Problems of Extragenital Pathology Department

Ю. В. Давидова, Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine

MD, Head of the Obstetrical Problems of Extragenital Pathology Department

References

  1. Babushkina A.V. «L-arginine in terms of evidence-based medicine.» Ukrainian Medical Journal, 6(2009):43-48.
  2. Yelsky V.N., Vatutin N.T., Kalinkina N.V., Salakhova A.M. «Role of dysfunction edoteliya in the genesis of cardiovascular diseases.» Journal of Medical Sciences of Ukraine, 14(2008):51-62.
  3. Slobodskoy V.A. «Role of L-arginine in the treatment of patients with cardiovascular disease.» Health of Ukraine, 13-14(2009):62.
  4. Wheeler T., Evans P.W., Anthony F.W., Godfrey K.M., Howe D.T. and Osmond C. «Relationship between maternal serum vascular endothelial growth factor concentration in early pregnancy and fetal and placental growth.» Hum. Reprod., 14(2009):1619-1623.
  5. Voronkov L.G., Paraschenyuk L.P., Lutsak E.A. «Quality of life in chronic heart failure: actual aspects.» Heart Failure, 3(2010):18-23.
  6. Mendes de Leon C.F., Grady K.L., Eaton C. «Quality of life in a diverse population of heart failure patients.» J. Cardiopulm. Rehabil. Prev., 29(2009):171-178.

Published

2014-10-20

How to Cite

Ліманська, А. Ю., Давидова, Ю. В., & Слободський, В. А. (2014). Impact of use Tivortin on life quality and condition of the fetus in pregnant women with heart failure. REPRODUCTIVE ENDOCRINOLOGY, (19), 37–39. https://doi.org/10.18370/2309-4117.2014.19.37-39

Issue

Section

Pregnancy and childbirth