Оптимизация менеджмента родильниц с травматическими повреждениями промежности

О. В. Грищенко; И. В. Лахно

doi:10.18370/2309-4117.2014.18.51-53

Authors

О. В. Грищенко Kharkiv Medical Academy of Postgraduate Education, Ukraine
И. В. Лахно Kharkiv Medical Academy of Postgraduate Education, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2014.18.51-53

Keywords:

perineal trauma, postpartum period, Depantol

Abstract

It was performed a study of the effectiveness of vaginal suppositories Depantol application for the treatment of women with perineal trauma. It was examined 124 patients after vaginal delivery and 94 from them had perineal tears of I–II degree. In the main group consisted of 48 mothers with perineal tears it was administered Depantol 1 suppository intravaginally daily for 10 days. In the women with perineal lesions it was marked an increase of pro-inflammatory cytokines and CRP level. It was associated with the inflammatory response and could contribute to the formation of fibrotic scars. On the 3 day examination it was found that hyperemia of the wound was absent in all parturients of the main group and in the comparison group it was noted in 37,0% of cases. The complete epithelization of the wound of the perineum has occurred on 7,5 ± 1,4 days in case of Depantol treatment and 11,2 ± 3,8 day in parturients of the comparison group. The usage of Depantol has allowed realizing a friendly approach to management of women with perineal tears confirmed by its clinical efficacy

Author Biographies

О. В. Грищенко, Kharkiv Medical Academy of Postgraduate Education

MD, Professor, Dean of Faculty of Pediatrics

И. В. Лахно, Kharkiv Medical Academy of Postgraduate Education

PhD, assistant professor of the Perinatology, Obstetrics and Gynecology Department

References

Ilina I.Y., Dobrokhotova J.E., Zhdanova M.S. «Optimization of treatment methods aimed at improving processes of collagen formation in women with connective tissue dysplasia.» Bulletin of Peoples’ Friendship University. «Medicine. Obstetrics and Gynecology», 5(2009):76-81.
Selihova M.S., Vdovin S.V., Kotovskaya M.V., Aghabekian N.V. «Modern approaches to the management of postpartum women with birth trauma.» Obstetrics and Gynecology, 5(2013):70-75
Selihova M.S., Kotovskaya M.V. Management of the postpartum period in women with soft tissue injuries of the birth canal.» Obstetrics and Gynecology, 6(2009):48-49.
Chegini N. «TGF-beta system: the principal profibrotic mediator of peritoneal adhesion formation.» Semin Reprod Med., 26(4) (2008):298-312.
de Silva K.L., Tsai P.J., Kon L.M. et al. «Third and fourth degree perineal injury after vaginal delivery: does race make a difference?» Hawaii J Med Public Health, 73(3) (2014): 80-83.
Fritel X. [Pelvic floor and pregnancy] Gynecol Obstet Fertil., 38(5) (2010):332-346.
Gallagher K., Migliaccio L., Rogers R.G. et al. «Impact of nulliparous women’s body mass index or excessive weight gain in pregnancy on genital tract trauma at birth.» J Midwifery Womens Health, 59(1) (2014):54-59.
Islam A., Hanif A., Ehsan A. et al. Morbidity from episiotomy.» J Pak Med Assoc, 63(6) (2013):696-701.
Ismail K.M., Kettle C., Macdonald S.E. et al. Perineal Assessment and Repair Longitudinal Study (PEARLS): a matched-pair cluster randomized trial.» BMC Med.,11(2013):209-215.
Peirce C., Murphy C., Fitzpatrick M. et al. «Randomised controlled trial comparing early home biofeedback physiotherapy with pelvic floor exercises for the treatment of third-degree tears (EBAPT Trial).» BJOG,120(10) (2013):1240-1247.