Analysis of histology and expression of sex hormone receptors er and pr in the ovaries at polycystic ovary syndrome

Authors

  • В. М. Запорожан Odessa National Medical University, Ukraine
  • Н. Н. Рожковская Odessa National Medical University, Ukraine
  • Ю. В. Онищенко Odessa National Medical University, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2014.18.9-12

Keywords:

polycystic ovary syndrome, infertility, estrogen and progesterone receptors, immunohistochemistry

Abstract

Histologic analysis of ovarian tissue at polycystic ovary syndrome (PCOS) identified specific markers that are pathogenic factors in the case of chronic anovulation. Immunohistochemical research of expression sex hormones receptors in the ovarian tissue in PCOS showed characteristic changes of the expression of estrogen (ER) and progesterone receptors (PR) in the stroma and follicles There was revealed that changes of the expression of sex hormones in the follicles and ovarian stroma can play the important role in the process of folliculogenesis and fertility for women with PCOS.

Author Biographies

В. М. Запорожан, Odessa National Medical University

MD, Professor, Academician of Academy of Medical Sciences of Ukraine, Rector, Head of the Obstetrics and Gynaecology Department № 1

Н. Н. Рожковская, Odessa National Medical University

MD, professor, Obstetrics and Gynecology Department number 1,

Ю. В. Онищенко, Odessa National Medical University

Postgraduate student of the Obstetrics and Gynecology Department № 1

References

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Published

2014-11-17

How to Cite

Запорожан, В. М., Рожковская, Н. Н., & Онищенко, Ю. В. (2014). Analysis of histology and expression of sex hormone receptors er and pr in the ovaries at polycystic ovary syndrome. REPRODUCTIVE ENDOCRINOLOGY, (18), 9–12. https://doi.org/10.18370/2309-4117.2014.18.9-12

Issue

No. 18 (2014)

Section

Scientific Studies

License

Copyright (c) 2014 В. М. Запорожан, Н. Н. Рожковская, Ю. В. Онищенко

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