Modern approaches to therapy of vulvovaginal candidiasis

Authors

  • И. В. Хамаганова Russian National Research University named after NI Pirogov, Russian Federation

DOI:

https://doi.org/10.18370/2309-4117.2013.12.60-64

Keywords:

vulvovaginal candidiasis, resistance to antifungal drugs, sertaconazole

Abstract

In the paper discusses the important aspects of pathogenesis, clinical manifestations, treatment of vulvovaginal candidiasis and mechanism of the development of resistance to antifungal drugs. The literature data and our own studies in 58 patients with vulvovaginal candidiasis led to the conclusion of the effi ciency and safety of Zalain suppositories (sertaconazole).

Author Biography

И. В. Хамаганова, Russian National Research University named after NI Pirogov

MD, professor, Department of Skin Diseases and Cosmetology, Medical Postgraduate Faculty

References

  1. Antonov AG, Prikhodko NA, Ancyrskaya AS, Rudakova AA, Prutnevich TV Treatment of fungal infection in very preterm infants // Russian Journal of Perinatology and Pediatrics. – 2012. – № 5. – P. 13–17.
  2. Bayramova GR Genital candidiasis from the standpoint of the practitioner // Cervix pathology and genital infectionP. Edited by VN Prilepskaya. Moscow, MEDpress-Inform, 2008. – P. 219–224.
  3. Gomberg MA Vaginal discharge: diff erential diagnosis and treatment of vulvovaginal candidiasis // Farmateka. – 2005. – № 2 (98). – P. 50–53.
  4. Karamova AE, Khamaganova IV, Piven NP, Kalinina LA Recurrent mycoses: the accompanying bacterial fl ora and effi ciency of Sertaconazole (Zalain) // Clinical Dermatology and Venereology. – 2009. – № 4. – P. 54–57.
  5. Karapetyan TE, Naskhletashvili IV, Tyutyunnik VL Vulvovaginal candidiasis: a modern approach to the problem // Russian Medical Journal. – 2011. – № 1. – P. 64–67.
  6. Lutsevich KA, Reshetko OV, Rogozhina IE, Lutsevich NF Clinical effi cacy of Sertaconazole (Zalain) in topical treatment of vulvovaginal candidiasis at pregnancy // Russian Medical Journal. – 2011. – № 20. – P. 1274–1277.
  7. Podzolkova NM, Nikitina TI Sertaconazole in women with recurrent vulvovaginal candidiasis // Russian Medical Journal. – 2010. – № 19. – P. 1221–1224.
  8. Tyutyunnik VL, Karapetyan TE, Balushkina AA Modern principles of prevention and treatment of vulvovaginal candidiasis // Russian Medical Journal. – 2010. – Vol. 18, № 19. – P. 1253–1256.
  9. Khamaganova IV, Karamova AE, Shekrota AG, Makushina ZV Sertaconazole in the treatment of microsporia of smooth leather // Clinical Dermatology and Venereology. – 2010. – № 3. – P. 32–35.
  10. Yutskovskaya AD, Kulagina LM, Bereznikov AM, Ivlieva ES, Paulov OM Epidemiological features of fungal infections in the region of Primorsky Krai and treatment // Russian Journal of Skin and Venereal Diseases. – 2007. – № 1. – P. 52–55.
  11. Borelli C, Korting HC, Bödeker RH, Neumeister C Safety and effi cacy of sertaconazole nitrate cream 2% in the treatment of tinea pedis interdigitalis: a subgroup analysis // CutiP. 2010. 85(2), P.107–P.111.
  12. Croxtall JD, Plosker GL Sertaconazole: a review of its use in the management of superfi cial mycoses in dermatology and gynaecology // Drugs, 2009. 69(3). P.339–359.
  13. Elewski BE, Cantrell WC An open-label study of the safety and effi cacy of sertaconazole nitrate in the treatment of seborrheic dermatitis // J Drugs Dermatol. 2011.10(8): 895–9.
  14. Carrillo-Muñoz AJ, Tur-Tur C, Cárdenes DC, Estivill D, Giusiano G10 Leber R, Fuchsbischler P, Klobučnikova V et al. Sertaconazole nitrate shows fungicidal and fungistatic activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton fl occosum, causative agents of tinea pedis / Antimicrob Agents Chemother. 2011. 55(9). P. 4420–4421.
  15. Kaur S, Sur R, Liebel FT, Southall MD Induction of prostaglandin D2 through the p38 MAPK pathway is responsible for the antipruritic activity of sertaconazole nitrate // J Invest Dermatol. 2010. 130(10) P. 2448–2456.
  16. Kircik LH. Observational evaluation of sertaconazole nitrate cream 2% in the treatment of pruritus related to tinea pedis // CutiP. 2009. 84(5) P. 279–283.
  17. Nyirjesy P, Sobel JD Genital mycotic infections in patients with diabetes // Postgrad. Med. 2013, 125(3), P. 33–46.
  18. Weinberg JM, Koestenblatt EK Treatment of interdigital tinea pedis: once-daily therapy with sertaconazole nitrate. J Drugs Dermatol. 2011 10(10). P. 1135–P. 1140.

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Published

2013-08-17

How to Cite

Хамаганова, И. В. (2013). Modern approaches to therapy of vulvovaginal candidiasis. REPRODUCTIVE ENDOCRINOLOGY, (12), 60–64. https://doi.org/10.18370/2309-4117.2013.12.60-64

Issue

No. 12 (2013)

Section

Inflammatory diseases

License

Copyright (c) 2014 И. В. Хамаганова

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