New approaches to the treatment of endometriosis

Authors

  • Т. Ф Татарчук Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine, Ukraine
  • Н. Ф. Захаренко Institute of Pediatrics, Obstetrics and Kiev City Hospital number 9, Ukraine
  • Т. Н. Тутченко Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2013.11.36-42

Keywords:

endometriosis, L-arginine, Tivortin

Abstract

The results of the study that involving 64 women with endometriosis have shown that the use in the treatment of L-arginine (the drug Tivortin) has a direct impact on the underlying factors that play role in the development and progression of endometriosis. It makes the use of non-hormonal drug promising in treatment of endometriosis andhas an important role in the prevention of its recurrence.

Author Biographies

Т. Ф Татарчук, Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine

MD, professor, corresponding member. NAMS of Ukraine, Deputy Director for Research, Head of Endocrine Gynecology

Н. Ф. Захаренко, Institute of Pediatrics, Obstetrics and Kiev City Hospital number 9

PhD, senior researcher of the Endocrine Gynecology Department

Gynecology of NAMS of Ukraine, Head of the Gynecology Department

Т. Н. Тутченко, Institute of Pediatrics, Obstetrics and Gynecology of NAMS of Ukraine

PhD, researcher of the Endocrine Gynecology Department

References

  1. Eskenazi B, Warner MLE pidemiology of endometriosis // ObstetGynecolClin North Am. – 1997. – 24: 235–58.
  2. Johnson N, Hummelshoj L Consensus on current management of endometriosis // Human Reproduction. – 2013. –Vol. 0. – N. 0. – Р. 1–17.
  3. Ziegler D, Borghese B Endometriosis and infertility: pathophysiology and management Review Article // The Lancet. – 2010. – Vol. 376. Issue 9742. – Р. 730–738.
  4. Bulun S Estrogen Receptor-β, Estrogen Receptor-α, and Progesterone Resistance in Endometriosis // SeminReprod Med. – 2010. – 28 (1). – Р. 36–43.
  5. Meng-Hsing Wu Tsai Prostaglandin E2: the master of endometriosis? / Meng-Hsing Wu,Chun-Wun Lu, Pei-Chin Chuang, Shaw-Jenq // Experimental Biology and Medicine. – 2010. – 235. – Р. 668–677.
  6. Capobianco A, Rovere-Querini P Endometriosis, a disease of the macrophage // Frontiers in Immunology and Inflammation. – 2013. – Vol. 4. – Р. 9–12.
  7. Fernando L, Carvalho P Oxidative stress biomarkers in patients with endometriosis: systematic review // Arch Gynecol Obstet. – 2012. – Р. 286: 103.
  8. WahI R, Chan S Identification of Cells with Colony-Forming Activity, Self-Renewal Capacity, and Multipotency in Ovarian Endometriosis // The American Journal of Pathology. – 2011. – Vol. 178. – Issue 6. – Р. 2832–2844.
  9. Sutton CJ Prospective, randomized, double-blind, controlled trial of laser laparoscopy in the treatment of pelvic pain associated with minimal, mild, and moderate endometriosis / Sutton CJ, Ewen SP, Whitelaw N, Haines P // FertilSteril. – 1994. – Vol. 62 (4). – Р. 696–700.
  10. Adamson GD Endometriosis classification: an update // CurrOpinObstet Gynecol. – 2011. – Vol. 23 (4). – Р. 213–20.
  11. Janssen EB Prevalence of endometriosis diagnosed by laparoscopy in adolescents with dysmenorrhea or chronic pelvic pain: a systematic review / EB Janssen, K Hoppenbrouwers, C Meuleman1, TD Hooghe // Hum. Reprod. Update first published online May 31, 2013.
  12. Laschke MW Vasculogenesis: a new piece of the endometriosis puzzle / MW Laschke, C Giebels, M Menger // Human Reproduction Update – 2011. – Vol. 17. – N. 5. – Р. 628–636
  13. Artini M, Ruggiero F, Papini G, Simi V Cela and AR Genazzani. – 2011. – 256 p.
  14. Taylor R Mechanistic and Therapeutic Implications of Angiogenesis in Endometriosis / R Taylor, Jie Yu, M Torres, A Schickedanz, J Park, M Mueller, N Sidell. – Reprod Sci. – 2009. – Vol. 16 (2). – Р. 140–146.
  15. Van A Langendonckt. Antiangiogenic and vascular-disrupting agents in endometriosis: pitfalls and promises / A Van Langendonckt, J Donnez, S Defre`re1, G Dunselman, P Groothuis // Molecular Human Reproduction. – 2008. – Vol. 14. – N. 5. – Р. 259–268.
  16. Gupta S Role of oxidative stress in endometriosis // Reproductive BioMedicine Online. – 2006. – Vol. 13. – N 1. – Р. 126–134.
  17. Chatterjee S Arginine metabolic pathways determine its therapeutic benefit in experimental heatstroke: Role of Th1/Th2 cytokine balance / S Chatterjee, S Premachandran, R Bagewadikar, S Bhattacharya, S Chattopadhyay, T Poduval // Nitric Oxide. – 2006. – Vol. 15. – Issue 4. – P. 408–416.
  18. Marroni A Consistent interethnic differences in the distribution of clinically relevant endothelial nitric oxide synthase genetic polymorphisms / A Marroni, I Metzger, D Souza-Costa, S Nagassaki, V Sandrim, R Correa // Nitric Oxide. – 2005. – Vol. 12. – Issue 3. – P. 177–182.
  19. Rogers M, D’Amato R Common Polymorphisms in Angiogenesis // Cold Spring Harbor Laboratory Press. – 2013.
  20. Kinugasa S Increased asymmetric dimethylarginine and enhanced inflammation are associated with impaired vascular reactivity in women with endometriosis / S Kinugasa, K Shinohara, A Wakatsuki // Atherosclerosis. – 2011. – Vol. 219. – Issue 2. – P. 784–788.
  21. Cayci T The levels of nitric oxide and asymmetric dimethylarginine in the rat endometriosis model / T Cayci, E Akgul, Y Kurt1 T Ceyhan, I Aydin, O Onguru, H Yaman, E Cakir // Journal of Obstetrics and Gynaecology Research. – 2011. – Vol. 37. – Issue 8. – P. 1041–1047.
  22. Noris M L-arginine depletion in preeclampsia orients nitric oxide synthase toward oxidant species / Noris M, Todeschini M, Cassis P, Pasta F, Cappellini A, Bonazzola S, Macconi D, Maucci R, Porrati F, Benigni A, Picciolo C, Remuzzi G // Hypertension. – 2004. – Vol. 43 (3). – P. 614–622.
  23. López-Jaramillo P Review: The role of the L-arginine-nitric oxide pathway in preeclampsia // TherAdvCardiovasc Dis. – 2008. – Vol. 2. – N. 4. – P. 261–275.
  24. Khan KN Role of prostaglandin E2 in bacterial growth in women with endometriosis // Hum Reprod. – 2012. – Vol. 27 (12). – P. 3417–3424.
  25. Stepanov YM Arginine in medical practice / Stepanov YM, Kononov IN, Zhurbina AI, Filippova AY // J. Academy of Medical Sciences of Ukraine. – 2004. – V. 10. – № 1. – P. 340–352.
  26. Babushkina AB L-arginine from the point of view of evidence-based medicine // Ukrainian Medical Journal. – 2009. – № 6 (74). – P. 21–30.
  27. Lisitsyna NV Medications that affect the synthesis nitric oxide and their place in the pathogenesis of preeclampsia therapy // Scientific Statement of the Belgorod State University. – 2010. – № 10. – Vol. 10. – P. 10–18.

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Published

2014-11-15

How to Cite

Татарчук, Т. Ф., Захаренко, Н. Ф., & Тутченко, Т. Н. (2014). New approaches to the treatment of endometriosis. REPRODUCTIVE ENDOCRINOLOGY, (11), 36–42. https://doi.org/10.18370/2309-4117.2013.11.36-42

Issue

No. 11 (2013)

Section

Gynecology

License

Copyright (c) 2014 Т. Ф Татарчук, Н. Ф. Захаренко, Т. Н. Тутченко

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