Uterine artery embolization

Literature review

Authors

  • K.D. Plaksiieva SI “O.M. Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”; State Scientific Institution “Center for Innovative Medical Technologies of the NAS of Ukraine”, Kyiv, Ukraine https://orcid.org/0000-0002-3021-4515
  • N.V. Kosei SI “O.M. Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”; State Scientific Institution “Center for Innovative Medical Technologies of the NAS of Ukraine”, Kyiv, Ukraine https://orcid.org/0000-0003-3085-3285
  • T.F. Tatarchuk SI “O.M. Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”; State Scientific Institution “Center for Innovative Medical Technologies of the NAS of Ukraine”, Kyiv, Ukraine https://orcid.org/0000-0002-5498-4143
  • O.A. Vlasenko ESC “Institute of Biology and Medicine” of Taras Shevchenko National University of Kyiv; endovascular surgeon, Verum Medical Center, Kyiv, Ukraine https://orcid.org/0000-0001-8899-9223
  • V.S. Solskyy SI “O.M. Lukyanova IPOG of the NAMS of Ukraine”, Kyiv, Ukraine https://orcid.org/0000-0002-6083-976X

DOI:

https://doi.org/10.18370/2309-4117.2022.65.14-22

Keywords:

uterine fibroids, uterine artery embolization, uterine-sparing technologies

Abstract

Uterine fibroids (UF) is an extremely common benign tumor of the female reproductive system. This pathology is often associated with symptoms that significantly impair the quality of life of a woman and her working capacity, and can also affect the ability to conceive and gestation. Today, we have in the arsenal of operational, drug and minimally invasive methods of UF treatment. One of the most researched and at the same time rather controversial methods of UF treatment is uterine artery embolization (UAE).
Literary sources were reviewed using the MEDLINE, PubMed and Web of Science databases for the period 2011–2021. The data related to the history of the technique development, its implementation, indications and contraindications for UAE, its effect on the UF symptoms and on fertility were systematized and presented in this review.
UAE as an independent method for the treatment of benign uterine tumors has 20 years of experience in the world and in Ukraine. The indications for UAE are symptomatic UF: profuse and/or prolonged menstruation, dysmenorrhea, compression of the pelvic organs, dyspareunia, frequent urination or urinary retention. Absolute contraindications for UAE are genital tract infections, pregnancy, doubts about the diagnosis, as well as contraindications to the use of X-ray contrast agents.
The effectiveness of UAE is assessed by the manifestations of UF symptoms and by the degree of fibroids size reduction. The average node reduction in the diameter is 2.2 cm. The clinical efficacy index is 81–96, 70–100 and 46–100% respectively in the treatment of abnormal uterine bleeding, pelvic pain and symptoms of compression of adjacent organs. There is a decrease in the node volume by 25–60% within 3–6 months.
Conclusions. UAE today is an effective and safe minimally invasive operation, which is a worthy alternative to hysterectomy and expands the possibilities of organ-preserving technologies if there is UF.

Author Biographies

K.D. Plaksiieva, SI “O.M. Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”; State Scientific Institution “Center for Innovative Medical Technologies of the NAS of Ukraine”, Kyiv

Graduate student, Endocrine Gynecology Department;
researcher, Department of Reproductive Health

N.V. Kosei, SI “O.M. Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”; State Scientific Institution “Center for Innovative Medical Technologies of the NAS of Ukraine”, Kyiv

MD, professor, chief researcher, Endocrine Gynecology Department;
Head of Department of Reproductive Health

T.F. Tatarchuk, SI “O.M. Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”; State Scientific Institution “Center for Innovative Medical Technologies of the NAS of Ukraine”, Kyiv

MD, professor, corresponding member of the NAMS of Ukraine, deputy director for research work, head of the Endocrine Gynecology Department;
Chief researcher, Department of Reproductive Health

O.A. Vlasenko, ESC “Institute of Biology and Medicine” of Taras Shevchenko National University of Kyiv; endovascular surgeon, Verum Medical Center, Kyiv

PhD, assistant, Internal Medicine Department

V.S. Solskyy, SI “O.M. Lukyanova IPOG of the NAMS of Ukraine”, Kyiv

PhD, senior researcher, Endocrine Gynecology Department

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Published

2022-08-09

How to Cite

Plaksiieva, K., Kosei, N., Tatarchuk, T., Vlasenko, O., & Solskyy, V. (2022). Uterine artery embolization: Literature review. REPRODUCTIVE ENDOCRINOLOGY, (65), 14–22. https://doi.org/10.18370/2309-4117.2022.65.14-22

Issue

No. 65 (2022)

Section

Uroginecology

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Copyright (c) 2022 К.Д. Плаксієва, Н.В. Косей, Т.Ф. Татарчук, О.А. Власенко, В.С. Сольський

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