Патогенетические аспекты лечения воспалительных заболеваний внутренних женских половых органов на современном этапе

И. В. Антоненко

doi:10.18370/2309-4117.2016.30.70-74

Authors

И. В. Антоненко Odesa National Medical University Clinic, Ukraine https://orcid.org/0000-0002-9037-6524

DOI:

https://doi.org/10.18370/2309-4117.2016.30.70-74

Keywords:

inflammatory diseases of internal female reproductive organs, miramistin, Тamistol

Abstract

The aim of this study was to investigate the efficacy of Тamistol drug in treatment of inflammatory diseases of internal female reproductive organs.

We observed 84 patients with inflammatory diseases of internal female reproductive organs at the age of 18 to 59 years. The women were divided into 2 groups: primary – 43 patients who received integrated treatment with anti-inflammatory Тamistol drug (active ingredient – miramistin) for 14 days, and the comparison group – 41 women who received the traditional anti-inflammatory therapy.

In the first phase, all patients of main and control group receiving anti-inflammatory therapy based on identified pathogens. For main group patients with vulvovaginal candidiasis in the complex treatment was included antifungal drug with systemic effects (fluconazole, itraconazole). In the control group patients with vulvovaginal candidiasis did not receive antifungal drug with systemic action. All patients with inflammatory diseases of internal female reproductive organs took drugs that improve microcirculation, metabolic and reparative processes. In the second therapy phase, all patients in both groups received yogurt postantibiotic for 1 month and locally lactoginal for 14 days.

Bacteriological analysis showed a significant decrease in the colonization degree of opportunistic pathogens in 40 (93%) main group patients. Normalization of bacteriological indicators was achieved in 28 (68.3%) comparison group patients, 7 (17.1%) women have unchanged, and 6 (14.6%) patients worsened performance by reducing the vaginal lactobacilli content.

Thus, study results showed that the conventional anti-inflammatory treatment, despite some effectiveness, increases vaginal dysbacteriosis, since the use of antimicrobials destroys lactobacilli. The combined use antifungal drug with systemic action and Тamistol drug in the complex therapeutic is highly effective for the treatment of inflammatory diseases of the internal female reproductive organs.

Author Biography

И. В. Антоненко, Odesa National Medical University Clinic

PhD, gynecologist

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