Genital prolapse in women of advanced age, complicated decubital ulcer view at the preoperative treatment


  • В. А. Бенюк National Medical University named after A.A. Bogomolets, Ukraine
  • Р. В. Довгалев Bogomolets National Medical University, Ukraine
  • Л. Д. Ластовецкая Bogomolets National Medical University, Ukraine
  • Т. В. Ковалюк Bogomolets National Medical University, Ukraine



genital prolapse, decubital ulcer, depantol, lavomax


Genital prolapse is a syndrome of pelvic floor prolapse and pelvic organs prolapse, leading to a breach of their functions. Severe prolapse is accompanied by restriction of movement of patients, severe sexual dysfunction, urinary disorders, development of severe psychological problems up to depression, and complicated by decubital ulcers (erosions) of the cervix and vagina in 18–32% of cases.

This article presents the results of preoperative treatment of decubital ulcers in 59 elderly women with genital prolapse. The study group consisted of 30 women with genital prolapse and verified cervical disease who underwent complex therapy including depantol (1 suppository 2 times/day every day intravaginal at night for 10 days) and lavomax (0.125 g first two days, and then 0.125 g in 48 hours, with 10 tablets per course). A control group included 29 patients with severe descent and prolapse of internal genital organs, complicated decubital ulcer of cervix who underwent conventional therapy duration of 10 days. The control group consisted of 20 healthy women aged 53–65 years.

Analysis of the treatment effectiveness showed that this scheme of complex therapy of decubital ulcers in patients with postmenopausal genital prolapse, which included depantol and lavomax on the conventional scheme has demonstrated its clinical efficacy in 96.4% of cases (total clinical remission to improve) at very good tolerability in 97.2% of cases. Adverse effects and side effects were not observed in any case.

The proposed therapy of decubital ulcers in postmenopausal women with severe genital prolapse in preoperative period allows in short time to achieve epithelialization of defect without rough scarring due to reparative effects on the tissue, to improve the quality of patients life and is an effective method of preoperative treatment for this category of patients.

Author Biographies

В. А. Бенюк, National Medical University named after A.A. Bogomolets

MD, Professor, Head

Obstetrics and Gynecology Department number 3

Р. В. Довгалев, Bogomolets National Medical University

Assistant of the Obstetrics and Gynecology Department №3

Л. Д. Ластовецкая, Bogomolets National Medical University

PhD, associate professor of the Obstetrics and Gynecology Department №3

Т. В. Ковалюк, Bogomolets National Medical University

PhD, assistant of the Obstetrics and Gynecology Department №3


  1. Beniuk, V.A., Lastovetska, L.D., Shcherba, E.A., et al. “Modern management of bacterial vaginosis in women at high risk.” Scientific and educational journal Progressive researches “Science & Genesis” Prague (Czech Republic) (2014): 7–8.
  2. Beniuk, V.A., Dyndar, E.A., Kovaliuk, T.V. “Bacterial vaginosis complicated vulvovaginal candidiasis. Current approaches to diagnosis and treatment.” Women’s Health 7 (2009): 132–6.
  3. Budakov, P.V., Strizhakov, A.N. “Methods of prevention, treatment and training for women with disorders of the vaginal microcenosis to delivery and gynecological operations.” Questions of Gynecology, Obstetrics, Perinatology 3.2 (2004): 39–42.
  4. Bulatov, R.D. Optimizing of preoperative preparation, choice of anesthesia method and postoperative care for transvaginal gynecological operations: thesis for the PhD degree. Ufa (2003): 119 p.
  5. Kulakov, V.I., Gurtovoi, B.L., Ankirskaya, A.S., Antonov, A.G. “Actual problems of antimicrobial therapy and prophylaxis of infections in obstetrics, gynecology and neonatology.” J Obstetrics and Gynecology 1 (2004): 3–6.
  6. Krasnopolskiy, V.I., Serova, O.F., Tumanova, V.A. “Impact of infections on women’s reproductive system.” Russian Gazette of Obstetrician- Gynecologist 5 (2004): 26–9.
  7. Prilepskaya, V.N. Cervical vaginal and vulva disease. Moscow. MEDpress-inform (2003): 320–30, 367–96.
  8. Radzinskiy, V.E. Perineologia. Moscow. Medical Information Agency (2006): 331 p.
  9. Radzinskiy, V.E., Ordiyants, I.M., Chetvertakova, E.S., Misuno O.A. “Two-stage treatment of vaginal infections.” Obstetrics and gynecology 5 (2011): 1–4.
  10. Hay, F. “Bacterial vaginosis.” Medicine 33.10 (2005): 58–61.
  11. Kościński, T., Friebe, Z., Stadnik, H., Drews, M.R. “Anatomical and functional results of a modified sacral perineocolporectopexy for extreme forms of complex pelvic organs prolapsed.” Ginekol Pol 86.6 (2015): 429–33.
  12. Moehrer, В., Hertal, A., Jackson, S. “Oestrogens for urinary incontinence in women.” Cochrane Database Syst Rev 2 (2003): CD001405.
  13. Thubert, T., Bakker, E., Fritel, X. “Pelvic floor muscle training and pelvic floor disorders in women.” Gynecol Obstet Fertil 43.5 (2015): 389–94. [Article in French]
  14. Wang, Y., Li, Q., Du, H., et al. “Uterine prolapse complicated by vaginal cancer: a case report and literature review.” Gynecol Obstet Invest 77.2 (2014): 141-4.



How to Cite

Бенюк, В. А., Довгалев, Р. В., Ластовецкая, Л. Д., & Ковалюк, Т. В. (2016). Genital prolapse in women of advanced age, complicated decubital ulcer view at the preoperative treatment. REPRODUCTIVE ENDOCRINOLOGY, (29), 28–33.