The choice of medication for treatment of patients with chronic pelvic inflammatory diseases

Authors

  • О. В. Грищенко Kharkiv Academy of Postgraduate Education, Ukraine
  • И. В. Лахно Kharkiv Medical Academy of Postgraduate Education, Ukraine
  • В. И. Останина Kharkiv Municipal Clinical Maternity House with Neonatological Hospital, Ukraine
  • Е. В. Милютин Kharkiv Municipal Clinical Maternity House with Neonatological Hospital, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2016.27.88-92

Keywords:

pelvic inflammatory diseases, chlamydia, azithromycin, hemomycin

Abstract

Patients with chronic pelvic inflammatory diseases are often exceeding 2/3 among women seeking for the obstetrician-gynecologist help. To determine the therapeutic strategy it is need clear ideas about the most common cause of pelvic inflammatory diseases and methods of their treatment. In practice, the most frequently are chlamydia and mycoplasma infection, gonorrhea rate is gradually reduced. Among the antibacterial agents with a wide spectrum of activity macrolides are the most popular in the treatment of uncomplicated forms of pelvic inflammatory diseases. Among them azithromycin has the best bio-availability, high efficiency and the possibility for pulse therapy. On the Ukrainian pharmaceutical market represented more than 20 azithromycin drugs. Hemomycin is the only azithromycin generic drug in Ukraine with establishing bioequivalence.

The comparative study of hemomycin efficiency (main group) and other generic azithromycin medications registered in Ukraine (comparison group) in the treatment of 124 patients with chronic salpingoophoritis and cervicitis of chlamydial etiology was performed.

After treatment in women of the main group there was almost complete reduction of clinical symptoms. In the comparison group positive dynamics was significantly less pronounced. In the main group the efficiency of chlamydial infection treatment was 100%, while in the comparison group 16.1% of cases marked failure. Restoration of normal vaginal biotope was reported in 95.6% of patients in the main group and in the comparison group in 23.2% of patients remained cocci flora.

Hemomycin is superior in their effectiveness comparatively to other generic azithromycin drugs with pulse therapy regimen application. The appointment of hemomycin provides complete elimination of chlamydial infection, the completion of the inflammatory tissue response, vaginal flora restoration and protective properties of cervical mucous. According to the pharmacoeconomic qualities and clinical efficiency hemomycin is the drug of choice for antibacterial therapy of genital chlamydiosis.

Author Biographies

О. В. Грищенко, Kharkiv Academy of Postgraduate Education

MD, Professor, Dean of Faculty of Pediatrics

И. В. Лахно, Kharkiv Medical Academy of Postgraduate Education

PhD, assistant professor of the Gynecology and Perinatology Department

References

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Published

2016-04-05

How to Cite

Грищенко, О. В., Лахно, И. В., Останина, В. И., & Милютин, Е. В. (2016). The choice of medication for treatment of patients with chronic pelvic inflammatory diseases. REPRODUCTIVE ENDOCRINOLOGY, (27), 88–92. https://doi.org/10.18370/2309-4117.2016.27.88-92

Issue

No. 27 (2016)

Section

Inflammatory diseases

License

Copyright (c) 2016 О. В. Грищенко, И. В. Лахно, В. И. Останина, Е. В. Милютин

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