Pathogenetic therapy of cervical intraepithelial neoplasia II-III


  • Л. І. Воробйова National Cancer Institute (Kyiv), Ukraine
  • В. В. Дунаєвська National Cancer Institute, Kyiv, Ukraine
  • А. М. Кошмеринська Zhytomyr Regional Oncology Center, Ukraine



human papillomavirus, cervical cancer, antiviral drugs, indole-3-carbinol, cervical intraepithelial neoplasia, Epigalin®


The secondary prevention of cervical cancer include detection and treatment of preinvasive forms of the disease, which includes cervical intraepithelial neoplasia and atypical cervix leucoplachia. 98% cases of this pathology are associated with human papillomavirus. Traditional surgical methods of treatment of cervical intraepithelial neoplasia do not always lead to the elimination of the virus, that cannot completely exclude the possibility of recurrence. The article shows the literature data and own observations about the possibility of drug therapy in complex therapy of neoplasia. It is accentuated that the using of antiviral and immune drugs, biologically active complexes consisting of medical actions can achieve higher efficiency in comparison with surgical methods.

Author Biographies

Л. І. Воробйова, National Cancer Institute (Kyiv)

MD, head of the Scientific and Research Department of Gynecologic Oncology;

Chief oncogynecologist of the Ministry of Health of Ukraine

В. В. Дунаєвська, National Cancer Institute, Kyiv

PhD, oncogynecologist

А. М. Кошмеринська, Zhytomyr Regional Oncology Center



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How to Cite

Воробйова, Л. І., Дунаєвська, В. В., & Кошмеринська, А. М. (2015). Pathogenetic therapy of cervical intraepithelial neoplasia II-III. REPRODUCTIVE ENDOCRINOLOGY, (24), 74–77.



Tumors and pretumoral pathology