Problem of vitamin D deficiency

В. Б. Зафт, О. В. Рыкова, А. А. Зафт, Ж. О. Клімова, І. В. Бойко, В. В. Галицька

Abstract


In the article the problem of vitamin D deficiency, and its significance for the human body are presented. Its main source is fortified foods and dietary supplements. Vitamin D is also produced in the body by the action on the skin of ultraviolet radiation. Low concentrations of vitamin associated with level of total mortality, cardiovascular diseases and cancer. It is proven protective effects of vitamin D in diseases of the skeletal system (rickets, osteoporosis, osteomalacia). Modern laboratory methods for diagnosis of deficiency of vitamin D, which are used in the laboratory of “Synevo Ukraine”, are presents.


Keywords


vitamin D; vitamin D deficiency; laboratory diagnostics

References


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GOST Style Citations


1. Holick, M.F. “Vitamin D deficiency.” N Engl J Med, 357(2007): 266–281.

2. Bishoff-Ferrari, H.A., Burckhardt, P., Quack-Loetscher, K., Gerber, B., еt al. “Vitamin D deficiency: Evidence, safety, and recommendations for the Swiss population.” Report written by a group of experts on behalf of the Federal Commission for Nutrition (FCN) 2012. Online access [www.iccidd.org/p142000804.html], last accessed 30 Apr 2015.

3. D awson-Hughes, B., Mithal, A., et al. “IOF positions tatement: vitamin D reccomendations for older adults.” Osteoporos INT, 21(7) (2010): 1151–1154.

4. Шварц, Г.Я. Витамин D и D-гормон. — М., 2005. — 152 с.

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6. Holick, M.F. “Resurrection of vitamin D deficiency and rickets.” J Clin Invest, 116(2006): 2062–2072.

7. Rajakumar, K., Greenspan, S.L., Thomas, S.B., Holick, M.F. “Solar ultraviolet radiation and vitamin D: a historical perspective.” Am J Public Health, 97(2007): 1746–1754.

8. Holick, M.F., Binkley, N.C., Bischoff-Ferrari, H.A., et al. “Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.” J Clin Endocrinol Metab, 96(2011): 1911–1930.

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14. D awodu, A.I., Tsang, R.C. “Maternal vitamin D status: effecton milk vitamin D content and vitamin D status of breast feeding infants.” Adv Nutr, 3(3) (2012): 353–361.

15. Rizzoli, R., et al. “Vitamin D supplementation in elderly or postmenopausal women: a 2013 update of the 2008 recommendations from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).” Current Medical Research & Opinion, 29(4) (2013): 1–9.

16. Balabolkin, M.I., Kreminskaya, V.M., Klebanov, E.M. “The role of oxidative stress in the pathogenesis of diabetic neuropathy and the possibility of correcting preparations α-lipoic acid.” Problems Endocrinology, 3(51) (2005): 22–32.

17. Dusso, A.S., Brown, A.J., Slatopolsky, E. “Vitamin D.” Am J Physiol Renal Physiol, 289(2005): 8–22.

18. Gomez de Tejada Romero M.J., Sosa Henriquez M., et al. “Position document on the requirements and optimum levels of vitamin D.” Rev Osteoporos Metabol Miner, 1(3) (2011): 53–64.





DOI: http://dx.doi.org/10.18370/2309-4117.2015.23.75-78

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ISSN 2411-1295 (Online), ISSN 2309-4117 (Print)