Mastodynia elimination at hormonal treatment of patients with uterine myoma

А. Л. Тихомиров, А. А. Леденкова

Abstract


High frequency (at 54,2%) of combination of uterine fi broids and benign mammary dysplasia may be due to their common etiology and pathogenesis.

A large amount of literature data that based on clinical studies show the eff ectiveness of herbal and homeopathic medicines in treatment of mastitis, that is especially important in their nomination in patients with uterine myoma.

Agnus castus is the most studied among the medicinal plants that have affi nity for the neuroendocrine system of a human and preparations on the basis of which (including Mastodynon) is eff ectively used for the treatment of latent hyperprolactinemia and mastodynia, premenstrual and menopausal syndromes.

Studies have shown that Mastodynon helps to reduce the pain associated with mastitis and premenstrual syndrome, and also reduces the swelling of the glandular component, so it can be recommended for the treatment of diff use form of mammary dysplasia. Mastodynon is also possible to use during the course of hormonal therapy in patients with uterine myoma to ensure maximum safety and comfort for the patient treatment process

Keywords


uterine fi broids; benign mammary dysplasia; Agnus castus; Mastodynon

References


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Kaunitz A.M. «Oral contraceptive health benefi ts: perception versus reality.» Contraception,. Vol.59 Suppl.1) (1999):29-33;

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von Fallois J., Etterli-Billenkamp U., Schindler E.M., Schindler A.E. «Danazol for treatment of fi brocystic mastopathy.» Zentralbl. Gynakol, 117(1995):457-465.

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Brugisser R., Burkard W., Simmen U., Schaff ner W. Phytotherapie, 20:3(1999):154-158.

Christoff el V., Spengler B., Abel G. et al. «Proceedings of the 6th Annual Symposium on complementary.» Health Care. UK., 199.

Du Mee V.A.C. Aust. J. Med. Herbalism, 5(1993): 63-65. Phytotherapie (Munchen) (1999).

Hoberg E. «Swiss Federal Institute of Technology.» Zurich (1999).

Kilicdag E.B., Tarim E., Bagis T. et al. Int. J. Gyn. Obstet, 85(2004):292-293.

Merz P.G., Gorkow C., Schrodter A. et al. Exp. Clin. Endocr. Diabet, 104(1996):447-453.

Pravidel. Novartis Pfarma GmbH Germany (2004).

Wuttke W., Gorkow Ch., Jarry H. Darmstadt: Steinkopff Verlag (1995):81-91.

Sliulz G., Speiser P., Schultz A.M. et al. «Agnus-castus extracts inhibit prolactin secretion of rat pituitary cells.» Horm. Metabol. Res., 25(1993):243-255.

Spengler В., Schmidt J., Porzel A., Christoff el V. «Isolation and characterization of cyclic diterpenes from BNO 1095 (Vitex agnus castus).» In preparation (1999).

Wuttke W., Gorkow C., Jarry H. «Dopaminergic compounds in Vitex agnus castus.» Loew D., Rietbrock N. (Hrsg). Phytopharmaka in forschung und klinischer Anwendung.» Darmstadt: Steinkopff (1995):81-91.

Atmaca M. Kumru, Tezcan S.E. «Fluoxetine Versus Vitex agnus kastus extrakt in the treatment of premenstrual disorder.» Hum. Psychopharmacol, 18:3(2003):191-195.

Breckwoldt M. «Endocrinology and Therapy of breast diseas.» Zentral BL. Gynakol, 112(1990):1097-1099.

Berger D. «Vitex agnus kastus: Unbeden Klichkeit and Wirksamkeit beim praemenstruallen Syndrom, Wirkprinzipien und Wirkmechanismen eines neuetwickelten Extraktes: Dissertation.» Phit-Naturwissenserliebe Fakultat.Besel (1998):Р. 220.

Castillo E., Garibay M., Mirabent F. «Eff ect of alfa dihydroergocriptine in patients with fi brocistiс breast disease.» Gynecol. Obstet. Mex., 74(2006):580-584.

Daniele C., Thompson Coon J. Piuler M.H., Ernst E. «Vitex agnus kastus a systematic review of adverse events.» Drug. Saf, 28(2005):319-332.

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Spengler B., Schmidt J., Porcel A. «Ilolation and characterization of cyclic diterpenes from BNO 1095 (Vitex agnus kastus).» In preparation (1999).

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Kaunitz A.M. «Oral contraceptive health benefi ts: perception versus reality.» Contraception,. Vol.59 Suppl.1) (1999):29-33;

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24. Brickell C.(ed). London: Dorling Kindersley (1989).

25. Brugisser R., Burkard W., Simmen U., Schaff ner W. Phytotherapie, 20:3(1999):154-158.

26. Christoff el V., Spengler B., Abel G. et al. «Proceedings of the 6th Annual Symposium on complementary.» Health Care. UK., 199.

27. Du Mee V.A.C. Aust. J. Med. Herbalism, 5(1993): 63-65. Phytotherapie (Munchen) (1999).

29. Hoberg E. «Swiss Federal Institute of Technology.» Zurich (1999).

30. Kilicdag E.B., Tarim E., Bagis T. et al. Int. J. Gyn. Obstet, 85(2004):292-293.

31. Merz P.G., Gorkow C., Schrodter A. et al. Exp. Clin. Endocr. Diabet, 104(1996):447-453.

32. Pravidel. Novartis Pfarma GmbH Germany (2004).

33. Wuttke W., Gorkow Ch., Jarry H. Darmstadt: Steinkopff Verlag (1995):81-91.

34. Sliulz G., Speiser P., Schultz A.M. et al. «Agnus-castus extracts inhibit prolactin secretion of rat pituitary cells.» Horm. Metabol. Res., 25(1993):243-255.

35. Spengler В., Schmidt J., Porzel A., Christoff el V. «Isolation and characterization of cyclic diterpenes from BNO 1095 (Vitex agnus castus).» In preparation (1999).

36. Wuttke W., Gorkow C., Jarry H. «Dopaminergic compounds in Vitex agnus castus.» Loew D., Rietbrock N. (Hrsg). Phytopharmaka in forschung und klinischer Anwendung.» Darmstadt: Steinkopff (1995):81-91.

37. Atmaca M. Kumru, Tezcan S.E. «Fluoxetine Versus Vitex agnus kastus extrakt in the treatment of premenstrual disorder.» Hum. Psychopharmacol, 18:3(2003):191-195.

38. Breckwoldt M. «Endocrinology and Therapy of breast diseas.» Zentral BL. Gynakol, 112(1990):1097-1099.

39. Berger D. «Vitex agnus kastus: Unbeden Klichkeit and Wirksamkeit beim praemenstruallen Syndrom, Wirkprinzipien und Wirkmechanismen eines neuetwickelten Extraktes: Dissertation.» Phit-Naturwissenserliebe Fakultat.Besel (1998):Р. 220.

40. Castillo E., Garibay M., Mirabent F. «Eff ect of alfa dihydroergocriptine in patients with fi brocistiс breast disease.» Gynecol. Obstet. Mex., 74(2006):580-584.

41. Daniele C., Thompson Coon J. Piuler M.H., Ernst E. «Vitex agnus kastus a systematic review of adverse events.» Drug. Saf, 28(2005):319-332.

42. Hoberg E., Sticher O., Orjala J.E., Meier B. «Diterpene aus Fgni-casti fructus und ihre Analytik.» Ztsehr. Phytother, 149(1999):P. 3.

43. Jarr H., Leonardt S., Wunke W. «Agnus kastus als dopaminerges. Wirkprinzip in Mastodynon.» N. Ztsehr. Phytother, 12(1991):77-82.

44. Sliutz G., Speiser P., Schultz A.M. «Agnus kastus extraks ingibit prolactin secrecion of pituitery cell.» Horm. Metabol. Res, 25(1993):243-255.

45. Spengler B., Schmidt J., Porcel A. «Ilolation and characterization of cyclic diterpenes from BNO 1095 (Vitex agnus kastus).» In preparation (1999).

46. Wunke W., Gorcow C., Jarry H. «Dopaminergie compounds in Vitex agnus kastus. Loew D., Rietbrock N. (Hrsg). Phytopharmaka in forschung und klinischer Anwendung.» Darmstadt: Steinkopf (1995):81-91.





DOI: http://dx.doi.org/10.18370/2309-4117.2014.19.86-90

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