Vitamin D: potential clinical decisions in doctor practice

Authors

  • Ю. І. Комісаренко National Medical University named after A.A. Bogomolets, Ukraine
  • М. І. Бобрик National Medical University named after A.A. Bogomolets, Ukraine
  • І. В. Сідорова LLC «ML «Dila», Ukraine
  • О. А. Бурка LLC «ML «Dila», Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2014.20.105-108

Keywords:

vitamin D3, anti-Mullerian hormone, pregnancy, fertility, polycystic ovary syndrome

Abstract

It is proved that vitamin D plays a role in the prevention and treatment of many diseases such as immunodeficiency status, anemia, diabetes melitus, various pathological conditions of the liver, gastrointestinal tract, cardiovascular system, tuberculosis, tumors of breast, bowel, etc. Also it was found that vitamin D modulates reproductive processes in women particularly affects steroidogenesis of estradiol and progesterone, and anti-Mullerian hormone in healthy women.
Therefore, at examining patient clinicians should determine the expediency of laboratory assays of the level of vitamin D.
According to the recommendation of the European Society of Endocrinology (2011) vitamin D deficiency is established at blood levels of its active metabolite 25(OH)D less than 20 ng/mL (< 50 nmol/l), failure –21–29 ng/ml (50–75 nmol/l).

Author Biographies

Ю. І. Комісаренко, National Medical University named after A.A. Bogomolets

MD, assistant professor, Endocrinology Department

М. І. Бобрик, National Medical University named after A.A. Bogomolets

PhD, assistant professor, Endocrinology Department

І. В. Сідорова, LLC «ML «Dila»

Medical director

О. А. Бурка, LLC «ML «Dila»

PhD, a specialist in medical marketing direction «Urogynecology»

References

  1. Povoroznyuk, V.V. “State of the problem of osteoporosis and other metabolic bone diseases in Ukraine.” News of Medicine and Pharmacy, 3(487) (2014): 10-13.
  2. Schwartz, G.J. Vitamin D and D-hormone. M: Anacharsis (2005): 152 p.
  3. Corbett, S.T., Hill, O., Nangia, A.K. “Vitamin D receptor found in human sperm.” Urol, 68(2006):1345-9.
  4. Lerchbaum, E., Obermayer-Pietsch, B. “MECHANISMS IN ENDOCRINOLOGY: Vitamin D and fertility: a systematic review.” Eur J Endocrinol, 166(2012): 765-778. May 1.
  5. Yamamoto, H., et al. “The caudal-related homeo-domain protein Cdx-2 regulates vitamin D receptor gene expression in the small intestine.” J. Bone Miner. Res, 14(2) (1999): 240-247.
  6. Lee, D.M.1, Tajar, A., Pye, S.R., Boonen; “EMAS study group. Association of hypogonadism with vitamin D status: the European Male Ageing Study.” Eur J Endocrinol, 166(1) (2012):77-85. Jan. DOI: 10.1530/EJE-11-0743. Epub 2011 Nov 2.
  7. Clarks, M. et al. “1,25-dihydroxyvitamin D3 target cells in immature pancreatic islets.“ Amer. J. Physiol, 253(1) Pt. 1(1987): E99-E105.
  8. Blomberg Jensen, M., Nielsen, J.E., Jorgensen, A., et al. “Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract.” Hum Reprod, 25(2010): 1303-11.
  9. Haussler, M.R. “Vitamin D receptors: nature and functuion.” Ann. Rev. Nutrition, 6(1986): 525-562.
  10. Isia, G., et al. “High prevalence of hypovitaminosis D in female type 2 diabetic population.” Diabetes care, 24(8) (2001): 1496.
  11. Lukyanova, E.M., Antypkin, Y.G., Omelchenko, L.I., Apuhovskaya, L.I. Vitamin D and its role in the health of children and pregnant women. K.: Aurora-print (2005): 229 p.
  12. Clinical Guidelines Authorized by: OGCCU King Edward Memorial Hospital Review Team: OGCCU Perth Western Australia Screening for and Treatment of Vitamin D Deficiency in Pregnancy Date Revised (2014). April.
  13. Yildizhau, R., Kurdolgu, M. “Serum 25-hydroxyvitamin D concentrations in obese and non-obese women with polycystic ovary syndrome.” Archives of
  14. Gynecology and obstetrics, 280(2009):559-563.
  15. Pittas, Ag., Lan, J., Dawson-Hughes, B. “The rolef vitamin D and calcium in type 2 diabets. A systematic review and meta-analysis.” Journal of Clinical Endocrinology and Metabolism, 92(2007):2017-2029.
  16. Absatarova, Y.S., Andreeva, E.N. “The role of vitamin D and melatonin in the pathogenesis of polycystic ovary syndrome.” Obesity and Metabolism, 1(2014).
  17. Holick, M.F., Binkley, N.C., Heike, A., et al. “Treatment, and Prevention of Vitamin D Deficiency: An Endocrine Society Clinical Practice Guideline.” J Clin Endocrinol Metab, 96(7) (2011):1911-30.

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Published

2014-12-19

How to Cite

Комісаренко, Ю. І., Бобрик, М. І., Сідорова, І. В., & Бурка, О. А. (2014). Vitamin D: potential clinical decisions in doctor practice. REPRODUCTIVE ENDOCRINOLOGY, (20), 105–108. https://doi.org/10.18370/2309-4117.2014.20.105-108

Issue

No. 20 (2014)

Section

Laboratory diagnosis

License

Copyright (c) 2015 Ю. І. Комісаренко, М. І. Бобрик, І. В. Сідорова, О. А. Бурка

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