Endogenous progesterone and progestins in physiological pregnancy, in prevention and treatment of its complications

В. Ф. Нагорная

Abstract


Progesterone has the main role in the mechanisms of successful pregnancy. In obstetric practice to support the pregnancy with a deficit of progesterone progestins (progesterone analogues) are used. In obstetric practices in Ukraine progesterone, micronized progesterone, dydrogesterone are used. Analysis of long-term results of administration of progestogens during pregnancy, enduring the criteria of evidence-based medicine, was performed only for dydrogesterone. The main indication for the dydrogesterone use in obstetric practice is a treatment and prevention of miscarriages.


Keywords


pregnancy; miscarriage; progesterone; dydrogesterone

References


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Bacg X, Saney T, Brechot MC et al. Intrahepatic cholestasis of pregnancy. Hepatology 1997; 26: 358–64.

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Suzar L, Carmichael et al. Maternal Progestin Intake and Risk of Hypospadias. Arch. Pediatr Adolesc Med. 2005; 159; 957–962.





DOI: https://doi.org/10.18370/2309-4117.2013.13.30-44

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