Deficiency of vitamin D among Ukrainian population: risk-factors of development

В. В. Поворознюк, Н. І. Балацька

Abstract


The article presents the results of epidemiological study the frequency of vitamin D deficiency among Ukraine population. It was shown that majority of examined has got a deficient in vitamin D (81.8%). 84,3% of peoples older 75 years old are suffered with vitamin D deficiency. The risk-factors of vitamin D deficiency for Ukrainian population are female gender, obesity (BMI over 35 kg/m2),underweight (BMIless than 18,5kg/m2), winter season and living notin the southern region of the country


Keywords


vitamin D deficiency; frequency; risk-factors of development; population of Ukraine

References


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Bikle DD Vitamin D: role in skin and hair / In: Feldman D, ed. Vitamin D. Vol 1. 2 nd ed. San Diego, Calif: Elsevier Academic Press. – 2005. – P. 609–630.

Holick MF High Prevalence of Vitamin D Inadequacy and Implications for Health / M.F. Holick // Mayo Clin Proc. – 2006. – Vol. 81 (3). – P. 353–373.

Holick MF The vitamin D content of fortified milk and infant formula/ M.F. Holick, Q. Shao, W. Liu, T. Chen // N Engl J Med. – 1992. – Vol. 326. – P. 1178–1181.

Prosser DE Enzymes involved in the activation and inactivation of vitamin D / D.E. Prosser, G. Jones // Trends in biochemical sciences. – 2004. – Vol. 29. – P. 664–673.

Gascon-Barre M The Vitamin D 25-Hydroxylase / M. Gascon-Barre // Elsevier. – 2005. – Vol. 1. P. 47–67.

Hewison M Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease/ M. Hewison, et al. // J Steroid Biochem Mol Biol. – 2007. – Vol. 103. – P. 316–321.

Holick MF Evaluation, treatment, and prevention of vitamin D deficiency: an edrocrine society clinical practice / M.F. Holick, N.C. Binkley, H.A. Bischoff-Ferrari et al. // J Clin Endocrinol Metab. – 2011. – Vol.96 (7). – P. 1911–193.

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Christakos S Newinsights into the mechanisms of vitamin D action / S.Christakos, P. Dhawan, Y. Liu, X. Peng, A. Porta // J Cell Biochem. – 2003. – Vol. 88. – P. 695–705.

Dusso AS Vitamin D / A.S. Dusso, A.J. Brown, E. Slatopolsky // Am J Physiol Renal Physiol. – 2005. – Vol. 289. – P. 8–28.

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Holick MF Vitamin D deficiency / M.F. Holick // N. Engl J Med. – 2007. – Vol. 357. – P. 266–281.

Holick MF Prevalence of vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy / M.F. Holick, E.S. Siris, N.

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Holik MF Age, vitamin D, and solar ultraviolet // M.F. Holik, L.Y. Matsuoka, J. Wortsman // Lancet. – 1989. – Vol. 2. – P. 1104–1105.

Wortsman J Decreased bioavailability of vitamin D in obesity / J. Wortsman, L.Y. Matsuoka, T.C. Chen et al. // Am J Clin Nutr. – 2000. – Vol. 72. – P. 690–693.

Zhou C Steroid and xenobiotic receptorand vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia / C. Zhou, M. Assem, J.C. Tay et al. // J Clin Invest. – 2006. – Vol. 116. – P. 1703–1712.

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GOST Style Citations


Tangpricha V Fortification of orange juice with vitamin D: a novel approach to enhance vitamin D nutritional health / V. Tangpricha, P. Koutkia, S.M. Rieke // Am J Clin Nutr. – 2003. – Vol. 77. – P. 1478–1483.

Bikle DD Vitamin D: role in skin and hair / In: Feldman D, ed. Vitamin D. Vol 1. 2 nd ed. San Diego, Calif: Elsevier Academic Press. – 2005. – P. 609–630.

Holick MF High Prevalence of Vitamin D Inadequacy and Implications for Health / M.F. Holick // Mayo Clin Proc. – 2006. – Vol. 81 (3). – P. 353–373.

Шварц Г.Я. Витамин D и D-гормон / Г.Я. Шварц // М.: Анахарсис, 2005. – 152 с.

Holick MF The vitamin D content of fortified milk and infant formula/ M.F. Holick, Q. Shao, W. Liu, T. Chen // N Engl J Med. – 1992. – Vol. 326. – P. 1178–1181.

Prosser DE Enzymes involved in the activation and inactivation of vitamin D / D.E. Prosser, G. Jones // Trends in biochemical sciences. – 2004. – Vol. 29. – P. 664–673.

Gascon-Barre M The Vitamin D 25-Hydroxylase / M. Gascon-Barre // Elsevier. – 2005. – Vol. 1. P. 47–67.

Hewison M Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease/ M. Hewison, et al. // J Steroid Biochem Mol Biol. – 2007. – Vol. 103. – P. 316–321.

Holick MF Evaluation, treatment, and prevention of vitamin D deficiency: an edrocrine society clinical practice / M.F. Holick, N.C. Binkley, H.A. Bischoff-Ferrari et al. // J Clin Endocrinol Metab. – 2011. – Vol.96 (7). – P. 1911–193.

Bringhurst TR Mineral metabolism / In: T.R. Bringhurst, M.B. Demay, P.R. Larson, H.M. Kronenberg, K.S. Polonsky, eds. Williams Textbook of Endocrinology. 10th ed. Philadelphia: WB Saunders. – 2003. – P. 1317–1320.

Heaney RP Functional indices of vitamin D status and ramifications of vitamin D deficiency / R.P. Heaney // Am J Clin Nutr. – 2004. – Vol. 80 (6 suppl). – P. 1706–1709.

Christakos S Newinsights into the mechanisms of vitamin D action / S.Christakos, P. Dhawan, Y. Liu, X. Peng, A. Porta // J Cell Biochem. – 2003. – Vol. 88. – P. 695–705.

Dusso AS Vitamin D / A.S. Dusso, A.J. Brown, E. Slatopolsky // Am J Physiol Renal Physiol. – 2005. – Vol. 289. – P. 8–28.

Bikle DD VITAMIN D: Newly Discovered Actions Require Reconsideration of Physiologic Requirements/ D. D. Bikle // Trends Endocrinol Metab. – 2010. – Vol. 21(6). – P. 375–384.

Holick MF Vitamin D deficiency / M.F. Holick // N. Engl J Med. – 2007. – Vol. 357. – P. 266–281.

Holick MF Prevalence of vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy / M.F. Holick, E.S. Siris, N.

Binkley, M.K. Beard et al. // J Clin Endocrinol Metab. – 2005. – Vol. 90. – P. 3215–3224.

Lips P The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation / P. Lips, D. Hosking, K. Lippuner, J.M. Norquist et al. // J Intern Med. – 2006. – Vol. 260. – P. 245–254.

Gordon CM Treatment of hypovitaminosis D in infants and toddlers / C.M. Gordon, A.L. Williams, H.A. Feldman et al. // J Clin Endocrinol Metab. – 2008. – Vol. 93. – P. 2716–2721.

De Luca H Overview of general physiologic features and functions of vitamin D / De Luca H // Am J Clin Nutr. – 2004. – Vol. 80 (6 Suppl). – P. 1689–1696.

Holick MF Vitamin D status: measurement, interpretation and clinical application / M.F. Holick // Ann Epidemiol. – 2009. – Vol. 19. – P. 73–78.

Bischoff-Ferrari HA Benefit-risk assessment of vitamin D supplementation / H.A. Bischoff-Ferrari, A. Shao, B. Dawson-Hughes et al. // Osteoporos Int. – 2010. – Vol. 21. – P. 1121–1132.

Pietras SM Vitamin D2 treatment for vitamin D deficiency and insufficiency for up to 6 years / S.M. Pietras, B.K. Obayan, M.H. Cai, M.F. Holick // Arch Intern Med. – 2009. – Vol. 169. – P. 1806–1808.

Holick MF The vitamin D epidemic and its health consequences / M.F. Holick // The Journal of nutrition. – 2005 (Suppl. Vitamin D, Sunlight, and Health) – P. 2739–2748.

Chapuy MC Healthy elderly French women living at home have secondary hyperparathyroidism and high bone turnover in winter: EPIDOS Study Group / M.C. Chapuy, A.M. Schott, P. Garnero, D. Hans et al. // J Clin Endocrinol Metab. – 1996. – Vol.81. – P. 1129–1133.

Heaney RP Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol / R.P. Heaney, K.M. Davies, T.C. Chen, M.F. Holick et al. // Am J Clin Nutr. – 2003. – Vol.77. – P. 204–210.

Thacher TD Nutritional rickets around the world: causes and future directions / T.D. Thacher, P.R. Fischer, M.A. Strand, J.M. Pettifor // Ann Top Paediatr. – 2006. – Vol. 26. – P. 1–16.

Holick MF Vitamin D: a millennium perspective / M.F. Holick // J. Cell Biochem. – 2003. – Vol. 88. – P. 296–307.

Matsuoka LY Sunscreens suppress cutaneous vitamin D3 synthesis / L.Y. Matsuoka, L. Ide, J. Wortsman et al. // J Clin Endocrinol Metab. – 1987. – Vol. 64. – P. 1165–1168.

Hintzpeter B Higher prevalence of vitamin D deficiency is associated with immigrant background among children and adolescents in Germany / B. Hintzpeter, C. Scheidt-Nave, M.J. Muller // J Nutr. – 2008 – Vol. 138. – P. 1482–1490.

Holik MF Age, vitamin D, and solar ultraviolet // M.F. Holik, L.Y. Matsuoka, J. Wortsman // Lancet. – 1989. – Vol. 2. – P. 1104–1105.

Wortsman J Decreased bioavailability of vitamin D in obesity / J. Wortsman, L.Y. Matsuoka, T.C. Chen et al. // Am J Clin Nutr. – 2000. – Vol. 72. – P. 690–693.

Zhou C Steroid and xenobiotic receptorand vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia / C. Zhou, M. Assem, J.C. Tay et al. // J Clin Invest. – 2006. – Vol. 116. – P. 1703–1712.

Adams JS Hypercalcemia caused by granulomaforming disorders / In: Favus M.J. ed. Primer on the metabolic bone diseases and disorders of mineral metabolism. 6th ed. Washington, DC // J.S. Adams, M. Hewison. – 2006. – P. 200–202.

Grey A Vitamin D repletion in patients with primary hyperparathyroidism and coexistent vitamin D insufficiency / A. Grey, J. Lucas, A. Horne, G Gamble // J Clin Endocrinol Metab. – 2005. – Vol. 90. – P. 2122–2126.





DOI: http://dx.doi.org/10.18370/2309-4117.2013.13.7-13

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