Deficiency of vitamin D among Ukrainian population: risk-factors of development

Authors

  • В. В. Поворознюк Gerontology Institute named after D.F. Chebotarev of Ukrainian NAMS, Ukraine
  • Н. І. Балацька D.F. Chebotarev Institute of Gerontology NAMS of Ukraine, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2013.13.7-13

Keywords:

vitamin D deficiency, frequency, risk-factors of development, population of Ukraine

Abstract

The article presents the results of epidemiological study the frequency of vitamin D deficiency among Ukraine population. It was shown that majority of examined has got a deficient in vitamin D (81.8%). 84,3% of peoples older 75 years old are suffered with vitamin D deficiency. The risk-factors of vitamin D deficiency for Ukrainian population are female gender, obesity (BMI over 35 kg/m2),underweight (BMIless than 18,5kg/m2), winter season and living notin the southern region of the country

Author Biographies

В. В. Поворознюк, Gerontology Institute named after D.F. Chebotarev of Ukrainian NAMS

MD, Professor, honoured worker of science and technology of Ukraine, Head of the Department of the Clinical Physiology and Pathology of the Musculoskeletal System

Н. І. Балацька, D.F. Chebotarev Institute of Gerontology NAMS of Ukraine

PhD

References

  1. Tangpricha V Fortification of orange juice with vitamin D: a novel approach to enhance vitamin D nutritional health / V. Tangpricha, P. Koutkia, S.M. Rieke // Am J Clin Nutr. – 2003. – Vol. 77. – P. 1478–1483.
  2. Bikle DD Vitamin D: role in skin and hair / In: Feldman D, ed. Vitamin D. Vol 1. 2 nd ed. San Diego, Calif: Elsevier Academic Press. – 2005. – P. 609–630.
  3. Holick MF High Prevalence of Vitamin D Inadequacy and Implications for Health / M.F. Holick // Mayo Clin Proc. – 2006. – Vol. 81 (3). – P. 353–373.
  4. Holick MF The vitamin D content of fortified milk and infant formula/ M.F. Holick, Q. Shao, W. Liu, T. Chen // N Engl J Med. – 1992. – Vol. 326. – P. 1178–1181.
  5. Prosser DE Enzymes involved in the activation and inactivation of vitamin D / D.E. Prosser, G. Jones // Trends in biochemical sciences. – 2004. – Vol. 29. – P. 664–673.
  6. Gascon-Barre M The Vitamin D 25-Hydroxylase / M. Gascon-Barre // Elsevier. – 2005. – Vol. 1. P. 47–67.
  7. Hewison M Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease/ M. Hewison, et al. // J Steroid Biochem Mol Biol. – 2007. – Vol. 103. – P. 316–321.
  8. Holick MF Evaluation, treatment, and prevention of vitamin D deficiency: an edrocrine society clinical practice / M.F. Holick, N.C. Binkley, H.A. Bischoff-Ferrari et al. // J Clin Endocrinol Metab. – 2011. – Vol.96 (7). – P. 1911–193.
  9. Bringhurst TR Mineral metabolism / In: T.R. Bringhurst, M.B. Demay, P.R. Larson, H.M. Kronenberg, K.S. Polonsky, eds. Williams Textbook of Endocrinology. 10th ed. Philadelphia: WB Saunders. – 2003. – P. 1317–1320.
  10. Heaney RP Functional indices of vitamin D status and ramifications of vitamin D deficiency / R.P. Heaney // Am J Clin Nutr. – 2004. – Vol. 80 (6 suppl). – P. 1706–1709.
  11. Christakos S Newinsights into the mechanisms of vitamin D action / S.Christakos, P. Dhawan, Y. Liu, X. Peng, A. Porta // J Cell Biochem. – 2003. – Vol. 88. – P. 695–705.
  12. Dusso AS Vitamin D / A.S. Dusso, A.J. Brown, E. Slatopolsky // Am J Physiol Renal Physiol. – 2005. – Vol. 289. – P. 8–28.
  13. Bikle DD VITAMIN D: Newly Discovered Actions Require Reconsideration of Physiologic Requirements/ D. D. Bikle // Trends Endocrinol Metab. – 2010. – Vol. 21(6). – P. 375–384.
  14. Holick MF Vitamin D deficiency / M.F. Holick // N. Engl J Med. – 2007. – Vol. 357. – P. 266–281.
  15. Holick MF Prevalence of vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy / M.F. Holick, E.S. Siris, N.
  16. Binkley, M.K. Beard et al. // J Clin Endocrinol Metab. – 2005. – Vol. 90. – P. 3215–3224.
  17. Lips P The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation / P. Lips, D. Hosking, K. Lippuner, J.M. Norquist et al. // J Intern Med. – 2006. – Vol. 260. – P. 245–254.
  18. Gordon CM Treatment of hypovitaminosis D in infants and toddlers / C.M. Gordon, A.L. Williams, H.A. Feldman et al. // J Clin Endocrinol Metab. – 2008. – Vol. 93. – P. 2716–2721.
  19. De Luca H Overview of general physiologic features and functions of vitamin D / De Luca H // Am J Clin Nutr. – 2004. – Vol. 80 (6 Suppl). – P. 1689–1696.
  20. Holick MF Vitamin D status: measurement, interpretation and clinical application / M.F. Holick // Ann Epidemiol. – 2009. – Vol. 19. – P. 73–78.
  21. Bischoff-Ferrari HA Benefit-risk assessment of vitamin D supplementation / H.A. Bischoff-Ferrari, A. Shao, B. Dawson-Hughes et al. // Osteoporos Int. – 2010. – Vol. 21. – P. 1121–1132.
  22. Pietras SM Vitamin D2 treatment for vitamin D deficiency and insufficiency for up to 6 years / S.M. Pietras, B.K. Obayan, M.H. Cai, M.F. Holick // Arch Intern Med. – 2009. – Vol. 169. – P. 1806–1808.
  23. Holick MF The vitamin D epidemic and its health consequences / M.F. Holick // The Journal of nutrition. – 2005 (Suppl. Vitamin D, Sunlight, and Health) – P. 2739–2748.
  24. Chapuy MC Healthy elderly French women living at home have secondary hyperparathyroidism and high bone turnover in winter: EPIDOS Study Group / M.C. Chapuy, A.M. Schott, P. Garnero, D. Hans et al. // J Clin Endocrinol Metab. – 1996. – Vol.81. – P. 1129–1133.
  25. Heaney RP Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol / R.P. Heaney, K.M. Davies, T.C. Chen, M.F. Holick et al. // Am J Clin Nutr. – 2003. – Vol.77. – P. 204–210.
  26. Thacher TD Nutritional rickets around the world: causes and future directions / T.D. Thacher, P.R. Fischer, M.A. Strand, J.M. Pettifor // Ann Top Paediatr. – 2006. – Vol. 26. – P. 1–16.
  27. Holick MF Vitamin D: a millennium perspective / M.F. Holick // J. Cell Biochem. – 2003. – Vol. 88. – P. 296–307.
  28. Matsuoka LY Sunscreens suppress cutaneous vitamin D3 synthesis / L.Y. Matsuoka, L. Ide, J. Wortsman et al. // J Clin Endocrinol Metab. – 1987. – Vol. 64. – P. 1165–1168.
  29. Hintzpeter B Higher prevalence of vitamin D deficiency is associated with immigrant background among children and adolescents in Germany / B. Hintzpeter, C. Scheidt-Nave, M.J. Muller // J Nutr. – 2008 – Vol. 138. – P. 1482–1490.
  30. Holik MF Age, vitamin D, and solar ultraviolet // M.F. Holik, L.Y. Matsuoka, J. Wortsman // Lancet. – 1989. – Vol. 2. – P. 1104–1105.
  31. Wortsman J Decreased bioavailability of vitamin D in obesity / J. Wortsman, L.Y. Matsuoka, T.C. Chen et al. // Am J Clin Nutr. – 2000. – Vol. 72. – P. 690–693.
  32. Zhou C Steroid and xenobiotic receptorand vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia / C. Zhou, M. Assem, J.C. Tay et al. // J Clin Invest. – 2006. – Vol. 116. – P. 1703–1712.
  33. Adams JS Hypercalcemia caused by granulomaforming disorders / In: Favus M.J. ed. Primer on the metabolic bone diseases and disorders of mineral metabolism. 6th ed. Washington, DC // J.S. Adams, M. Hewison. – 2006. – P. 200–202.
  34. Grey A Vitamin D repletion in patients with primary hyperparathyroidism and coexistent vitamin D insufficiency / A. Grey, J. Lucas, A. Horne, G Gamble // J Clin Endocrinol Metab. – 2005. – Vol. 90. – P. 2122–2126.
  35. Schwartz GJ. Vitamin D and D-hormone / G.J. Schwartz // Moscow: Anaharsis, 2005. – 152 p.

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Published

2013-11-17

How to Cite

Поворознюк, В. В., & Балацька, Н. І. (2013). Deficiency of vitamin D among Ukrainian population: risk-factors of development. REPRODUCTIVE ENDOCRINOLOGY, (13), 7–13. https://doi.org/10.18370/2309-4117.2013.13.7-13

Issue

No. 13 (2013)

Section

Analytical review

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Copyright (c) 2014 В. В. Поворознюк, Н. І. Балацька

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