Current approaches to the prevention and treatment of iron deficiency anemia in pregnancy in the XXI century

Ю. В. Давыдова, А. А. Огородник

Abstract


Pregnantare in particular risk of developing iron-deficiency anemia as a result of the increasing need in trace elements during gestation. According to WHO recommendations for the prevention of iron deficiency anemia, pregnant as early as possible, no later than the I trimester and during hole pregnancy appointed iron supplements in a dose of 60 mg iron in a day. Among the oral medication for the treatment of iron deficiency anemia should be preferred non-ionic iron preparations on the basis of the hydroxide polymaltose complex of ferric iron.

Keywords


iron deficiency anemia; pregnancy; prevention; iron; iron supplements

References


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Pena-Rosas JP, Viteri FE Effects and safety of preventive oral iron or iron+folic acid supplementation for women during pregnancy / CochraneDatabaseofSystematicReviews. – 2009; 4: CD004736.

Zhou LM, Yang WW, Hua JZ, Deng CQ, Tao X, Stoltzfus RJ Relation of hemoglobin measured at di erent times in pregnancy to preterm birth and low birth weight in Shanghai, China // Am J.Epidemiol. – 1998; 148: 998–1006.

Aivazyan GG Ed ectofcombineduseo£ ronsupplementswithantioxidantsonlipidperoxidationandant ioxidantdefenseintheblood of experimental animals // Dissertation for the degree of Candidate of Medical Sciences, 2009.


GOST Style Citations


1. Айвазян Г.Г. Влияние комбинированного применения препаратов железа с антиоксидантами на показатели перекисного окисления липидов и антиоксидантной защиты в крови экспериментальных животных //Автореферат дисс. на степень к. мед. н., 2009.

2. Bader D, Kugelman A, Maor-Rogin N et al. The role of high-dose oral iron supplementation during erythropoietin therapy for anemia of prematurity // J. Perinatol. – 2001. – № 21(4). – Р. 215–20.

3. Beaumont C Molecular mechanisms of iron homeostasis // Med Sci. – 2004. – № 20(1). – Р. 68–72.

4. Cogswell ME, Looker AC, Pfei er CM et al. Assessment of iron de£ ciency in US preschool children and nonpregnant females of childbearing age: National Health and Nutrition Examination Survey, 2003–2006 // Am. J. Clin. Nutr. – 2009; 89: 1334–1342.

5. Erichsen K, Ulvik RJ, Grimstad T, Berstad A, Berge RK, Hausken T E ects of ferrous sulphate and non-ionic iron-polymaltose complex on markers of oxidative tissue damage in patients with in ammatory bowel disease // Aliment. Pharmacol.Ther. – 2005. – № 1, 22(9). – Р. 831–8.

6. Fleming RE Advances in understanding the molecular basis for the regulation of dietary iron absorption // Curr. Opin. Gastroenterol. – 2005; 21(2): 201–6.

7. IdoateGastearena MA, Gil AG, Azqueta A, Coronel MP, Gimeno M. A comperative study on the gastroduodenal tolerance of diferent antianemic preparation // Hum. Exp. Toxicol. – 2003. – № 22(3). – Р. 137–41.

8. Isler M, Delibas N, Guclu M, Guldekin F, Sutcu R, Bahceci M, Kosar A Superoxide dismutase and glutathione peroxidase in erytrocytes of patient with iron de£ cieny anemia: ects of di erent treatment modalities // Croatian medical journal. – 2002. – № 43(1). – Р. 16–19.

9. Kurtoglu E, Ugor A, Baltaci AK and Undar L Efect of iron supplementation on oxidative stress and antioxidant status in iron deficiency anemia // Biol. Trace. Elem. Res. – 2003. – № 96 (1–3). – Р. 117–124.

10. Pena-Rosas JP, Viteri FE Effects and safety of preventive oral iron or iron+folic acid supplementation for women during pregnancy / CochraneDatabaseofSystematicReviews. – 2009; 4: CD004736.

11. Zhou LM, Yang WW, Hua JZ, Deng CQ, Tao X, Stoltzfus RJ Relation of hemoglobin measured at di erent times in pregnancy to preterm birth and low birth weight in Shanghai, China // Am J.Epidemiol. – 1998; 148: 998–1006.





DOI: http://dx.doi.org/10.18370/2309-4117.2013.10.46-50

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