Metafolin in combined oral contraceptives – investments in reproductive welfare. World news: modern contraception – new opportunity of pregravidarum preparing

Authors

  • Т. В. Галина Peoples’ Friendship University of Russia, Russian Federation

DOI:

https://doi.org/10.18370/2309-4117.2013.10.15-22

Keywords:

folic acid, combined oral contraceptives, pregnancy, Metafolin

Abstract

This article is a review of the material on the key studies that demonstrated in women of reproductive age, especially considering pregnancy the efficacy and safety of oral contraceptives containing ethinylestradiol and drospirenone combined with the active form of folic acid. Such combination provide increased folate levels in red blood cells and in plasma, reduced homocysteine levels in the blood plasma, thereby significantly reduce the probability of abnormal fetus development. The expediency of receiving data combined drugs proved not only for contraception, but also for pregravidarum preparing – to normalize the folate status of women requires minimum 16 weeks of exogenous folate intake, because the probability of pregnancy is very high right after the withdrawal combined oral contraceptives.

Author Biography

Т. В. Галина, Peoples’ Friendship University of Russia

Department of Obstetrics and Gynecology with course of Perinatology

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Published

2013-11-14

How to Cite

Галина, Т. В. (2013). Metafolin in combined oral contraceptives – investments in reproductive welfare. World news: modern contraception – new opportunity of pregravidarum preparing. REPRODUCTIVE ENDOCRINOLOGY, (10), 15–22. https://doi.org/10.18370/2309-4117.2013.10.15-22

Issue

Section

Gynecology