Treatment of disorders in menopausal women with hyperproliferative processes of reproductive system


  • Л. І. Бутіна Donetsk National Medical University, Ukraine



menopausal disorders, hyperproliferative processes of reproductive system, treatment


Objective. Evaluate the effectiveness of treatment of disorders in menopausal women with hyperproliferative processes of reproductive system (HPPRS).

Materials and methods. The treatment was performed in 36 women after hormone prevention (HP) of neurovegetative and psycho-emotional disorders in menopause (NVPDM) and in 31 women after naturally menopause aged 48 to 60 with the signs of HPPRS according to the data of ultrasound uterine and the results of histology investigations of mucosal scrapings from the uterus. The control group consisted of 35 healthy women of the same age category. The treatment was carried out by the appointment of elaborated complex of preparation, which included a combined homeopathic preparation, a preparation from the microalgae Spirulina platensis, pectin and an anxiolytic agent with the active substance mebicar. To assess the effectiveness of therapy, hormonal homeostasis was studied before and after treatment.

Results of the study. In 31 women with menopausal HPPRS after naturally menopause the increase of FSH was observed in 1.4 times, estradiol – in 1.4 times, compared with healthy women. After HP use in 36 women the level of FSH decreased in 2.2 times, but the level of estrogens increased in 1.9 times, progesterone level increased in 1.4 times compared with healthy women. After treatment in women with naturally menopause the levels of FSH increased on 36%, estradiol – on 29%. In women after HP and treatment the level of estrogens decreased in 3.2 times, the level of FSH increased in 1.4 times but it level decreased on 35% compared with healthy women. But most of the symptoms of NVPDM in women of both subgroups disappeared.

Conclusions: In women with HPPRS was observed a greater level of sex hormones than healthy ones, which is provided by the increased production of gonadotropic hormone and is accompanied by the development of NVPDM. The use of HP and treatment reduces the intensity of NVPDM on account of gonadotropins level reduction compared with healthy women.

Author Biography

Л. І. Бутіна, Donetsk National Medical University

PhD, associate professor of Obstetrics and Gynaecology Department


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How to Cite

Бутіна, Л. І. (2017). Treatment of disorders in menopausal women with hyperproliferative processes of reproductive system. REPRODUCTIVE ENDOCRINOLOGY, (37), 70–74.



Management of menopause