Possibilities for therapy of a comorbidity of uterine myoma and benign breast dysplasias

Authors

  • В. Е. Радзинский Peoples’ Friendship University of Russia, Moscow, Russian Federation
  • И. М. Ордиянц Peoples’ Friendship University of Russia, Moscow, Russian Federation
  • М. Н. Масленникова City Clinical Hospital No. 12, Moscow, Russian Federation
  • Е. А. Павлова Peoples’ Friendship University of Russia, Moscow, Russian Federation
  • В. В. Карданова Peoples’ Friendship University of Russia, Moscow, Russian Federation

DOI:

https://doi.org/10.18370/2309-4117.2017.36.86-89

Keywords:

benign breast dysplasia, uterine myoma

Abstract

Objective. To improve the reproductive health of women with benign breast dysplasia (BBD) and uterine myoma, by elaborating a differentiated approach to preventing and treating comorbid diseases.

Subject and methods. The investigation included 175 women with concomitant genital diseases and BBD who were treated at the Gynecology Unit of the City Clinical Hospital No. 12, Moscow. The results of their examination and differentiated treatment for comorbid diseases of the uterus and breast were analyzed.

Results. The altered ratio of steroid hormone levels as absolute or relative hyperestrogenemia underlies the pathogenesis of BBD in women with uterine myoma. The elaborated differentiated approach allows quality of life to be improved of 43.4% of patients with combined diseases of the mammary glands and genitals, to reduce the progression and recurrence of BBD in patients with uterine myoma from 36.7 to 15.9%.

Conclusion. The findings strongly suggest that the women of this category must form a special follow-up gynecological group and their treatment must be a preventive measure against the progression and recurrence of BBD.

Author Biographies

В. Е. Радзинский, Peoples’ Friendship University of Russia, Moscow

MD, professor, head of Obstetrics and Gynecology Department with Course of Perinatology

И. М. Ордиянц, Peoples’ Friendship University of Russia, Moscow

MD, professor of Obstetrics and Gynecology Department with Course of Perinatology

М. Н. Масленникова, City Clinical Hospital No. 12, Moscow

PhD, resident physician 

Е. А. Павлова, Peoples’ Friendship University of Russia, Moscow

Postgraduate student of Obstetrics and Gynecology Department with Course of Perinatology

В. В. Карданова, Peoples’ Friendship University of Russia, Moscow

Postgraduate student of Obstetrics and Gynecology Department with Course of Perinatology

References

  1. Gynecology: National leadership Ed. by V.I. Kulakov, I.B. Manukhin, G.M. Savelieva. Moscow. GEOTAR-Media (2007): 1072 p.
  2. Suturina, L.V., Popova, L.N. “Effect of bromocriptine and cyclodinone on clinical symptoms and prolactin levels with reproductive age hyperprolactinemia.” Questions of gynecology, obstetrics and perinatology 9.2 (2010): 41–3.
  3. Khaskhanova, L.H. Forecasting, early diagnosis and treatment of non-cancerous diseases of the mammary glands after surgical treatment of gynecological diseases. Thesis abstract for MD degree. Moscow (2003): 47 p.
  4. Konovalova, V.N. “Discussion questions of tactics of conducting women with benign diseases of mammary glands.” Effective pharmacotherapy in obstetrics and gynecology 6 (2009): 6–12.
  5. Prilepskaya, V.N., Tagieva, T.T. “Fibrous-cystic disease of mammary glands: the possibility of non-hormonal therapy.” Medline-Express 5 (2008): 10–7.
  6. Filippov, O.S. Benign mammary gland diseases. Moscow. MEDPress-Inform (2008): 112 p.
  7. Radzinsky, V.E. Medicinal plants in obstetrics and gynecology. 8th ed. Moscow. EKSMO (2008): 317 p.
  8. Rozhkova, N.I., Meskikh, E.V. “Mastodinone: possibilities of application at various forms of mastopathy.” Tumors of the female reproductive system 4 (2008): 46–7.
  9. Radzinsky, V.E. Mammary glands and gynecological diseases. Moscow. Status Praesens (2010): 304 p.

Downloads

Published

2017-09-14

How to Cite

Радзинский, В. Е., Ордиянц, И. М., Масленникова, М. Н., Павлова, Е. А., & Карданова, В. В. (2017). Possibilities for therapy of a comorbidity of uterine myoma and benign breast dysplasias. REPRODUCTIVE ENDOCRINOLOGY, (36), 86–89. https://doi.org/10.18370/2309-4117.2017.36.86-89

Issue

No. 36 (2017)

Section

Tumors and pretumoral pathology

License

Copyright (c) 2017 В. Е. Радзинский, И. М. Ордиянц, М. Н. Масленникова, Е. А. Павлова, В. В. Карданова

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.