National consensus on the management of patients in menopause

Authors

  • Тобі де Вільєрс The International Menopause Society; National Osteoporosis Foundation of South Africa,
  • Т. Ф Татарчук Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine, Ukraine
  • Н. В. Авраменко Запоріжжя, Ukraine
  • О. В. Булавенко Вінниця, Ukraine
  • В. А. Габаль Київ, Ukraine
  • О. В. Бурлака Київ, Ukraine
  • І. Ю. Ганжий Запоріжжя, Ukraine
  • Н. І. Геник Івано-Франківськ, Ukraine
  • О. В. Грищенко Харків, Ukraine
  • А. М. Громова Полтава, Ukraine
  • І. Ю. Головач Київ, Ukraine
  • І. Д. Гюльмамедова Київ, Ukraine
  • З. М. Дубоссарська Дніпропетровськ, Ukraine
  • Ю. О. Дубоссарська Дніпропетровськ, Ukraine
  • Г. О. Ісламова Київ, Ukraine
  • Г. С. Ісаєва Харків, Ukraine
  • О. О. Єфименко Київ, Ukraine
  • В. П. Квашенко Київ, Ukraine
  • Н. В. Косей Київ, Ukraine
  • С. В. Неспрядько Київ, Ukraine
  • І. П. Мазур Київ, Ukraine
  • В. Г. Марічереда Одеса, Ukraine
  • Л. Б. Маркін Львів, Ukraine
  • Є. І. Мітченко Київ, Ukraine
  • Н. Ю. Педаченко Київ, Ukraine
  • А. І. Попович Львів, Ukraine
  • Н. М. Рожковська Одеса, Ukraine
  • В. С. Свінцицький Київ, Ukraine
  • Г. Б. Семенина Львів, Ukraine
  • І. І. Смоланка Київ, Ukraine
  • Т. М. Тутченко Київ, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2016.27.8-25

Keywords:

consensus, Association of Gynecologists-Endocrinologists of Ukraine, climacteric, menopause, perimenopause, postmenopausal period, menopausal hormone therapy

Abstract

This document provides an overview of existing diagnosis and treatment methods of menopausal disorders in women, proposed algorithms for diagnosis and treatment of this disease to prevent heart diseases, osteoporosis and improve the quality of ukrainian women life.

Climacteric is a physiological transition period in a woman’s life during which the reproductive system involutive processes against the age-related changes are dominated in the body, and characterized by reduction of menstrual and generative function due to genetically programmed cessation of ovarian function.

There are 4 periods of menopause: menopausal transition period, menopause, perimenopause and menopause.

No need for hormonal laboratory research to diagnosis of perimenopause and menopause for most healthy women aged over 45 with the following features: vasomotor symptoms on a background of irregular menstruation in perimenopause; absence of menstruation for the last 12 months or appearance of menopausal symptoms after hysterectomy at menopause.

The most common symptoms of menopause are vasomotor symptoms (hot flashes, night sweats, palpitations, labile blood pressure); psychological (emotional lability, depression, anxiety, irritability, sleep disturbances, poor memory and concentration); general physical symptoms (asthenia, headache, pain in muscles and joints, skin discomfort); urogenital and sexual (vaginal itching, burning, dryness and dyspareunia, frequent and urgent urination, decreased libido).

The only pathogenetically effective method for the correction of menopausal disorders is menopausal hormone therapy. For this therapy are used natural estrogen (17β-estradiol, estradiol valerate, estriol) in combination with progestins (dydrogesterone) or androgens. It is possible parenteral (injections), transdermal, vaginal and oral hormone introduction.

To correct the climacteric syndrome, urogenital disorders are used short courses of menopausal hormone therapy (for 1–5 years). For the prevention and treatment of osteoporosis menopausal hormone therapy lasts over 3 years if necessary, in combination with a bisphosphonate.

Author Biographies

Тобі де Вільєрс, The International Menopause Society; National Osteoporosis Foundation of South Africa

Moderator, MD, professor, Vice-president; Vice-president

Т. Ф Татарчук, Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine

MD, professor, corresponding member. NAMS of Ukraine, Deputy Director for Research, Head of Endocrine Gynecology

Н. В. Авраменко, Запоріжжя

Доктор медичних наук, професор

О. В. Булавенко, Вінниця

Доктор медичних наук, професор

О. В. Бурлака, Київ

Кандидат медичних наук

І. Ю. Ганжий, Запоріжжя

Доктор медичних наук, професор

Н. І. Геник, Івано-Франківськ

Доктор медичних наук, професор

О. В. Грищенко, Харків

Доктор медичних наук, професор

А. М. Громова, Полтава

Доктор медичних наук, професор

І. Ю. Головач, Київ

Доктор медичних наук, професор

І. Д. Гюльмамедова, Київ

Доктор медичних наук, професор

З. М. Дубоссарська, Дніпропетровськ

Доктор медичних наук, професор

Ю. О. Дубоссарська, Дніпропетровськ

Доктор медичних наук, професор

Г. О. Ісламова, Київ

Кандидат медичних наук 

Г. С. Ісаєва, Харків

Кандидат медичних наук 

О. О. Єфименко, Київ

Кандидат медичних наук 

В. П. Квашенко, Київ

Доктор медичних наук, професор

Н. В. Косей, Київ

Доктор медичних наук

С. В. Неспрядько, Київ

Кандидат медичних наук 

І. П. Мазур, Київ

Доктор медичних наук, професор

В. Г. Марічереда, Одеса

Доктор медичних наук, професор

Л. Б. Маркін, Львів

Доктор медичних наук, професор

Є. І. Мітченко, Київ

Доктор медичних наук, професор

Н. Ю. Педаченко, Київ

Доктор медичних наук, професор

А. І. Попович, Львів

Кандидат медичних наук 

Н. М. Рожковська, Одеса

Доктор медичних наук, професор

В. С. Свінцицький, Київ

Доктор медичних наук, професор

Г. Б. Семенина, Львів

Доктор медичних наук

І. І. Смоланка, Київ

Доктор медичних наук, професор

Т. М. Тутченко, Київ

Кандидат медичних наук 

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2016-04-05

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де Вільєрс, Т., Татарчук, Т. Ф., Авраменко, Н. В., Булавенко, О. В., Габаль, В. А., Бурлака, О. В., Ганжий, І. Ю., Геник, Н. І., Грищенко, О. В., Громова, А. М., Головач, І. Ю., Гюльмамедова, І. Д., Дубоссарська, З. М., Дубоссарська, Ю. О., Ісламова, Г. О., Ісаєва, Г. С., Єфименко, О. О., Квашенко, В. П., Косей, Н. В., Неспрядько, С. В., Мазур, І. П., Марічереда, В. Г., Маркін, Л. Б., Мітченко, Є. І., Педаченко, Н. Ю., Попович, А. І., Рожковська, Н. М., Свінцицький, В. С., Семенина, Г. Б., Смоланка, І. І., & Тутченко, Т. М. (2016). National consensus on the management of patients in menopause. REPRODUCTIVE ENDOCRINOLOGY, (27), 8–25. https://doi.org/10.18370/2309-4117.2016.27.8-25

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No. 27 (2016)

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National consensus

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Copyright (c) 2016 Тобі де Вільєрс, Т. Ф Татарчук, Н. В. Авраменко, О. В. Булавенко, В. А. Габаль, О. В. Бурлака, І. Ю. Ганжий, Н. І. Геник, О. В. Грищенко, А. М. Громова, І. Ю. Головач, І. Д. Гюльмамедова, З. М. Дубоссарська, Ю. О. Дубоссарська, Г. О. Ісламова, Г. С. Ісаєва, О. О. Єфименко, В. П. Квашенко, Н. В. Косей, С. В. Неспрядько, І. П. Мазур, В. Г. Марічереда, Л. Б. Маркін, Є. І. Мітченко, Н. Ю. Педаченко, А. І. Попович, Н. М. Рожковська, В. С. Свінцицький, Г. Б. Семенина, І. І. Смоланка, Т. М. Тутченко

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