Diagnosis and treatment of abnormal uterine bleeding

Authors

  • Т. Ф Татарчук Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine, Ukraine
  • Н. В. Косей Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine, Ukraine
  • Н. А. Редько Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine, Ukraine
  • В. А. Джупин Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2014.19.22-32

Keywords:

abnormal uterine bleeding, tranexamic acid, Tranexam

Abstract

Comparative characteristic of the Tranexam effi cacy in women with abnormal uterine bleedings (AUB) in the absence of anatomic pathology was studied.

The study included 60 women with AUB, which were divided into 3 groups: the fi rst group consisted of 20 women with heavy menstrual bleeding, the second group – 20 patients with AUB on the background of uterine leiomyoma, the third group – 20 women with AUB on the background of adenomyosis.

Tranexam 500 mg 3 times a day from the fi rst to the fi fth day of the menstrual cycle for three months was appointed for secondary prevention of AUB. Iron therapy performed in all groups during the study if hemoglobin levels were less than 110 g/l.

At 1 and 3 months of preventive treatment monitoring was done.

During the studies it was proved the Tranexam eff ectiveness in the treatment as well as in the prevention of AUB in patients with heavy menstrual bleeding, uterine leiomyoma and adenomyosis. Hemostatic eff ect of the Tranexam is most pronounced realized in patients with uterine leiomyoma. Side eff ects were not registered

Author Biographies

Т. Ф Татарчук, Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine

MD, professor, corresponding member. NAMS of Ukraine, Deputy Director for Research, Head of Endocrine Gynecology

Н. В. Косей, Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine

MD, Chief researcher at the Department of Endocrine Gynecology

Н. А. Редько, Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine

Graduate student at the Department of Endocrine Gynecology

В. А. Джупин, Institute of Pediatrics, Obstetrics and Gynecology, NAMS of Ukraine

Graduate student at the Department of Endocrine Gynecology

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Published

2014-10-20

How to Cite

Татарчук, Т. Ф., Косей, Н. В., Редько, Н. А., & Джупин, В. А. (2014). Diagnosis and treatment of abnormal uterine bleeding. REPRODUCTIVE ENDOCRINOLOGY, (19), 22–32. https://doi.org/10.18370/2309-4117.2014.19.22-32

Issue

Section

Clinical lecture