Modern nonhormonal possibilities of treatment of polycystic ovary syndrome in obese women
Keywords:polycystic ovary syndrome, obesity, adipocytokines
The aim of the study was to explore the use of multicomponent herbal preparation in treatment of polycystic ovary syndrome (PCOS) in women with obesity and normal levels of ovarian androgens.
We examined 120 patients with PCOS and 30 healthy women. All subjects were divided into subgroups according to the use of a component of a treatment complex. The authors found that the use of the developed approach with the inclusion in the scheme of treatment multicomponent herbal preparation gives possible normalize the function of adipose tissue and improve its relationship with the pituitary-adrenal and pituitar-ovarian systems, normalize the menstrual cycle. COC use in patients with obesity and normal androgen level leads only to some cosmetic effect and the regulation of the cycle for the period of treatment, without affecting or impairing the other types of metabolism, leading to destabilization, deepening of existing violations and the transition from functional into organic changes.
- Mukherjee S Polycystic ovary syndrome. Review/ Mukherjee S, Maitra A// Indian J Med Res. – 2010. – Vol.131. – P. 743–760.
- Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group 2004 Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)// Hum Reprod. – 2004. – Vol.19. – P.41-47.
- Lindsay RS Adiponectin and development of type 2 diabetes in the Pima Indian population / Lindsay RS, Funahashi T, Hanson RL [et al.] // Lancet. –2002. – Vol. 360. – P.57–58.
- Iniguez G Adiponectin levels in the first two years of life in a prospective cohort: relations with weight gain, leptin levels and insulin sensitivity / Iniguez G, Soto N, Avila A [et al.] // J. Clin. Endocrinol. Metab. – 2004. – Vol. 89. – P. 5500–5503.
- Ducluzeau PH Glucose-to-insulin ratio rather than sex hormone-binding globulin and adiponectin levels is the best predictor of insulin resistance in nonobese women with polycystic ovary syndrome / Ducluzeau PH, Cousin P, Malvoisin E [et al.] // Ibid. – 2003. – Vol. 88. – P. 3626–3631.
- Yilmaz M Serum resistin and adiponectin levels in women with polycystic ovary syndrome / Yilmaz M, Bukan N, Dtvirci H [et al.] // International Society of Gynecological Endocrinology. – 2009. – №. 32/4. – P. 68–74.
- Gevorgyan MAClinic, diagnosis and treatment of polycystic ovary syndrome / MA Gevorgyan, IB Manukhin, LB Studenaya [etc.] // ZHROAG. – 2008, № 4. – P. 3–20.
- Gluhov NV Diseases associated with polycystic ovary syndrome and metabolic syndrome / NV Gluhov, SJ Chubrieva, NA Belyakov // Efferent Therapy. – 2007. – Vol.13. – № 1. – P. 17–19.
- Grishchenko VI Polycystic ovary syndrome as a cause of endocrine infertility / Grishchenko VI, Grishchenko NG, Zagrebelnaya IV [etc.] // Medical Aspects of Women’s Health. – 2010. – № 1 (28.) – P. 5–12.
- Gopchuk EN Optimizing the diagnosis of polycystic ovary syndrome / E. Gopchuk // Proceedings of the Association of Obstetricians of Ukraine. – K.: Іntermed, 2011. – P. 189–194.
- Dedov II Endocrinology / Dedov II, GA Melnichenko. – Moscow: Triada-X, 2008. – 289 p.
- Naumenko VG Hyperandrogenism status / VG Naumenko // Medical Aspects of Women’s Health. – 2011. – № 1 (40). – P. 5–102.
- Zykova TD Metabolic features of polycystic ovary syndrome in women with normal and overweight / TD Zykova, AV Strelkova, BA Savenko, GA Melnichenko // Diabetes. – 2003. – № 1 (18). – P. 16–21.
- Tatarchuk TF Adipose tissue and the reproductive system of women / Tatarchuk TF, Cossey NV, Ganji IY // Health Protection of Ukraine. – 2008. – № 24/1. – P. 14–16.
- Shilin DE Polycystic Ovary Syndrome Diagnostic International Consensus (2003) and the modern ideology therapy / DE Shilin // Consilium Medicum. – 2004. – T. 06, № 9. – P. 27–31.
- Svetlakov AV Leptin and blood lipid profile in women with different types of obesity / Svetlakov AV, Yamanova MV, Filippov OS, Mahalova NA // Problems of Reproduction. – 2001. – № 6. – P. 29–32.
- Koval SN Adipose tissue adiponectin hormone and its role in the pathogenesis of the metabolic syndrome and cardiovascular diseases. Hypoadiponectinemia as a therapeutic target (review) / Koval SN, Snegursky IA // Journal of NAMS of Ukraine. – 2011. – V. 17, № 2. – P. 174–185.
- Dedov II Polycystic ovary syndrome and metabolic syndrome / Dedov II, Butrova SA // Obesity and Metabolism. – 2006. – № 1. – P. 30–40.
How to Cite
Copyright (c) 2014 Т. Ф Татарчук, І. Ю. Ганжий, Н. Ю. Педаченко, І. М. Капшук
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.