An experience of local drugs using in a treatment of urogenital trichomoniasis

Authors

  • Г. М. Бондаренко Institute of Dermatology and Venereology of the NAMS of Ukraine, Kharkiv, Ukraine
  • Ю. В. Щербакова Institute of Dermatology and Venereology of the NAMS of Ukraine, Kharkiv, Ukraine
  • И. Н. Никитенко Institute of Dermatology and Venereology of the NAMS of Ukraine, Kharkiv, Ukraine
  • В. Б. Чирва City Children’s Clinical Hospital № 24, Ukraine

DOI:

https://doi.org/10.18370/2309-4117.2014.16.49-55

Keywords:

urogenital trichomoniasis, Osarbon, ornidazole

Abstract

Urogenital trichomoniasis is an actual medical and social problem. It requires an active searching of new effective therapeutic regimens with modern parenteral drugs in combination with topical application using. It were conducted the studies (involving 50 patients with trichomoniasis and the control group of 15 women) of suppositories Osarbon in combination with parenteral ornidazole using in order to the effectiveness increasing of urogenital trichomoniasis therapy. The results showed high clinical efficacy Osarbon.

As a result, it was propose a complex treatment with the Osarbon use for patients with urogenital trichomoniasis.

References

Batkaev, E.A. «Urogenital trichomoniasis.» The Practitioner, 12 (2002): 64-70.

Bondarenko, G.M. Nikitenko, I.N. «New method of treatment of urogenital trichomoniasis in women.» Dermatologіya and venerologіya, 1 (2005): 78-82.

WHO «Global strategy for the prevention of sexually transmitted infections and control 2006-2015.» World Health Organization, (2007) 70 p.

Volkoslavskaya, V.N. Gutnev, A.L. «About On the sexually transmitted infections morbidity in Ukraine.» Clinical Immunology, Allergology, Іnfectology,1 (2011): 1-3.

Hasanov, T.A. «Parasitosis – a risk factor for inflammatory diseases of the pelvic.» Medical Parasitology and parasitic diseases, 1(2002): 3-8.

Gomberg, M.A. Solovyov, A.M. «How to choose the best drug for the trichomoniasis treatment.» Sexually transmitted infections. Overview, 2(2003)

Ermolenko, D.K. Isakov, V.A. Ribalkin, S.B. Smirnova, T.S. Zakharkov, Y.F. «Urogenital trichomoniasis: A Manual for Physicians.» St. Petersburg – Veliky Novgorod, (2007) 96 p.

Kaljuzhnaja, L.D. Gorbasenko, N.V. «Use of oral and vaginal drug «Trihopol» in the treatment of urogenital trichomoniasis and bacterial vaginosis.» Ukrainian Journal of dermatology, venerology, kosmetology, 1 (16 ) (2005): 94-97

Kissinа, V.I. «Clinical aspects and treatment of urogenital trichomoniasis with drug of 5- nitroimidazoles.» Consilium Medicum, 5 (3) (2003): 162-164.

Kissinа,V.I. «Urogenital trichomoniasis: problems and its solutions.» STI, 6 (2001): 14-17.

Kissinа, V.I. Kanisheva, E. «Inflammatory diseases of the pelvic organs in women and their connection with sexually transmitted infections. Diagnostics, treatment, prevention. Part II.» Journal of Dermatology and Venereology, 4(2002): 16-23.

Krasovsky, V.M. «Metronidazole, tinidazole, nimorazol, tenonitrozol, ornidazole in the treatment of patients with chronic urogenital trichomoniasis.» Men’s Health, 1(2008): 26-30.

Kopylov, V.M. Bochkarev, E.G. Gabby, V.M. «Urogenital trichomoniasis: actual questions of diagnostics and treatment: A guide for Physicians.» M.: Medical, (2001) 40 p.

Kuntcevich, L.D. Dubkov, I.A. Borshchevskaya, R.P. et al. «The role of obligate anaerobic flora in women with urogenital infectious diseases.» Russian Journal of Skin and Venereal Diseases, 1(2001): 56-59.

Mavrov, G.I. Nagorny, A.E. Chinov, G.P. «Sexually transmitted infections, and the problem of sexual and reproductive health.» Clinical Immunology, Allergology, Іnfectology, 1(2010): 5-14.

Mavrov, G.I. Ivashchenko, L.V. Nikitenko, I.N. «Urogenital trichomoniasis: new opportunities of topical immunomodulatory therapy.» Dermatology and venereology, 3(53) (2011): 69-77.

Mavrov, G.І. Stepanenko, V.І. Chіnov, G.P. Nіkіtenko, І.N. «Urogenіtalny trichomoniasis: new approaches to diagnostics and treatment: methodological recommendations.» Kiev (2004) 22 p.

Mavrov, I.I. «Sexually transmitted disease. Guide for doctors, interns and students.» Kharkiv: Fact (2002) 789 p.

Mikhailov, A.V. Hasanov, T.A. «The prevalence of urogenital trichomoniasis and features of its laboratory diagnostics in women with chronic inflammatory diseases of the pelvic organs.» STI, 2(2000): 26-29.

Molochkov, V.A. «Urogenital trichomoniasis and associates uretrogenycal infections (epidemiology, clinical manifestations, diagnostics, treatment, prevention).» Russian Journal of Skin and Venereal Diseases, 3(2000): 48-56.

In charge of publication Golubchikov M.V «Indicators of treatment and diagnostic care for patients with skin and venereal diseases in Ukraina.» Center of medical Statistics MOH of Ukraine, K (2013):110.

Romankova, O.I. Shupenko, M.M. «Urogenital trichomoniasis in women: a modern perspective on the problem and possible perspectives of its resolution.» Ukrainian Journal of dermatology, venerology, kosmetology, 3(2002): 83-92.

Rumin, D.V. «The role of Trichomonas vaginalis in the pathogenic microbiocenoses formation of human urogenital tract.» Bulletin of Postgraduate Medical Education, 3(2001): 16-20.

Chіnov, G.P. «The prevalence and clinical characteristics of chlamydia and trichomoniasis – of two the most widespread genital infections (An overview of current literature data and indicators of statistical reporting).» Ukrainian Journal of dermatology, venerology, kosmetology, 1(16) (2005): 74-81.

Alvarez-Sanchez, M.E. Avila-Gonzalez, L Becerril-Garcia, C. et al. «A novel cysteine proteinase (CP65) of Trichomonas vaginalis involved in cytotoxicity.» Departamento de Patologia Experimental, Mexico, 07360, D.F. Mexico /Microb Pathog, 28(4) (2000): 193-202.

Claeys, P Gonzales, M. et al. «Prevalence and risk factors of sexually transmitted infections and cervical neoplasia in women’s health clinics in Nicaragua.» Sex. Transm. Infect, 78(3) (2002): 204-207.

Mann, J.R. Mcdermott, S. Barnes, T.L. Hardin, J. Bao, H. Zhou L. «Trichomoniasis in pregnancy and mental retardation in children.» Ann Epidemiol, 19(12) (2009): 891-893. Dec.

Rendon Maldonado, J.G. Espinosa Cantellano, M. Gonzalez Robles, A. Martinez Palomo A. «Trichomonas vaginalis: in vitro phagocytosis of lactobacilli, vaginal epithelial cells, leukocytes and erythrocytes.» Exp Parasitol, 89 (2) (1998): 241-250.

Mann, J.R. McDermott, S. Barnes, T.L. Hardin, J. Bao, H. Zhou, L. «Trichomoniasis in pregnancy and mental retardation in children.» Ann Epidemiol, 19(12) (2009): 891-9. Dec.

Schwebke, J.R. Hook, E.W. «High rates of Trichomonas vaginalis among men attending a sexually transmitted diseases clinic: Implications for screening and urethritis management.» Journal of infectious diseases, 188(2003): 465-468.

Schmid, G. Narcisi, E. Mosure, D. Secor, W.E. Higgins, J. Moreno, H. «Prevalence of metronidazole-resistant Trichomonas vaginalis in a gynecology clinic.» Journal of reproductive medicine, 46(2001): 545-459.

Upcoft, R. et al. «Drug targets and mechanisms of resistance in the anaerobic protozoa.» Clinic. Microb. Rev., 14(2001): 150-64.

Published

2014-07-11

Issue

Section

Inflammatory diseases

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